Radiothérapie Moléculaire et Innovation Thérapeutique (RaMo-IT)

Présentation du laboratoire

L'unité Radiothérapie moléculaire focalise ses travaux de recherche sur la réponse aux radiations ionisantes selon 5 axes , 1) La mort cellulaire , 2) L'inflammation et la réponse immunologique , 3) Le microenvironnement tumoral et le métabolisme, 4) La pharmacomodulation et l'innovation technologique , 5) La recherche translationnelle. Ces différents axes de recherches ont pour but de proposer de nouvelles thérapies anti cancéreuses en améliorant sa détection (facteur de prédiction) et en proposant un meilleur pronostic en rendant la radiothérapie plus efficace.

Les 20 dernières publications

Titre Auteurs Date de publication Source
CANTO-RT: One of the Largest Prospective Multicenter Cohort of Early Breast Cancer Patients Treated with Radiotherapy including Full DICOM RT Data Sofia Rivera 01/02/2023 Cancers
Cytofluorometric characterization of the myeloid compartment of irradiated mouse tumors Marine Gerbé De Thoré, Lydia Meziani, Eric Deutsch, Michele Mondini 01/01/2023 Methods in Cell Biology
Radiotherapy as a means to increase the efficacy of T-cell therapy in solid tumors Pierre Antoine Laurent, Lydia Meziani, Eric Deutsch 01/01/2023 OncoImmunology
Chronic intermittent hypoxia, a hallmark of obstructive sleep apnea, promotes 4T1 breast cancer development through endothelin-1 receptors Mélanie Minoves, Sylvain Kotzki, Emeline Lemarié, Sophie Bouyon, Brigitte Gonthier, Jean Louis Pépin, Anne Briançon-Marjollet, Diane Godin-Ribuot 01/12/2022 Scientific Reports
Favorable safety profile of moderate hypofractionated over normofractionated radiotherapy in breast cancer patients: a multicentric prospective real-life data farming analysis Eric Deutsch, Sofia Rivera 01/12/2022 Radiation Oncology
Immune checkpoint-targeted antibodies: a room for dose and schedule optimization? Christophe Maritaz, S. Broutin, A. Paci 01/12/2022 Journal of Hematology and Oncology
COMBING: Clustering in Oncology for Mathematical and Biological Identification of Novel Gene Signatures Enzo Battistella, Roger Sun, Theo Estienne, Marvin Lerousseau, Sergey Nikolaev, Emilie Alvarez Andres, Alexandre Carré, Stephane Niyoteka, Charlotte Robert, Eric Deutsch 01/11/2022 IEEE/ACM Transactions on Computational Biology and Bioinformatics
Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation Giuseppe Arena, Eric Deutsch 31/10/2022 Frontiers in Oncology
Radiomics to evaluate interlesion heterogeneity and to predict lesion response and patient outcomes using a validated signature of CD8 cells in advanced melanoma patients treated with anti-PD1 immunotherapy Roger Sun, Marvin Lerousseau, Jade Briend-Diop, Théophraste Henry, Alexandre Carré, Adrien Laville, Anthony Hamaoui, Pierre Antoine Laurent, Angela Rouyar, Charlotte Robert, Eric Deutsch 28/10/2022 Journal for ImmunoTherapy of Cancer
Immune-related arthritis following pelvic radiation therapy in a patient with lung cancer receiving long-term immune checkpoint blocker treatment: Case report Eric Deutsch, A. Levy 24/10/2022 Frontiers in Immunology
Immuno-radiotherapy: A review of the rationale, recent clinical developments and future prospects Eric Deutsch 01/10/2022 Cancer/Radiotherapie
Practice changing clinical trials in radiation oncology in 2022 Sofia Rivera 01/10/2022 Cancer/Radiotherapie
Apport et méthodologies innovantes des essais de phase I en oncologie thoracique : des phases 1 aux essais BASKET/plateforme Christophe Massard 01/10/2022 Revue des Maladies Respiratoires Actualites
Radiotherapy-Related Dose and Irradiated Volume Effects on Breast Cancer Risk Among Hodgkin Lymphoma Survivors Cristina Veres, Ibrahima Diallo 01/09/2022 Journal of the National Cancer Institute
Imaging approaches and radiomics: toward a new era of ultraprecision radioimmunotherapy? Eric Deutsch 01/07/2022 Journal for ImmunoTherapy of Cancer
Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium Cyrus Chargari 01/07/2022 Biology
Establishing a benchmark of diversity, equity, inclusion and workforce engagement in radiation oncology in Europe – An ESTRO collaborative project Anne Gasnier 01/06/2022 Radiotherapy and Oncology
PD-1 iNhibitor and chemotherapy with concurrent IRradiation at VAried tumor sites in advanced Non-small cell lung cAncer: the Prospective Randomized Phase 3 NIRVANA-Lung Trial A. Levy 01/05/2022 Clinical Lung Cancer
The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals Eric Deutsch 01/04/2022 Cancer Discovery
How to Improve SBRT Outcomes in NSCLC: From Pre-Clinical Modeling to Successful Clinical Translation Marina Milic, Michele Mondini, Eric Deutsch 01/04/2022 Cancers

Nombre de publications du laboratoire par domaine scientifique (2016-2021)

Chaque publication du laboratoire peut être rangée dans une ou plusieurs disciplines scientifiques : la figure ci-dessus présente le nombre de publications du laboratoire pour chaque discipline de la classification ASJC (Elsevier)