Radiothérapie Moléculaire et Innovation Thérapeutique (RaMo-IT)

Laboratory presentation

The molecular radiotherapy unit focuses its research on the response to ionizing radiation by 5 axes, 1) Cell death, 2) Inflammation and immunological response, 3) Tumor microenvironment and metabolism, 4) Pharmacomodulation and technological innovation, 5) Translational research. The aim of these various research axes is to propose new anti-cancer therapies by improving its detection (prediction factor) and by proposing a better prognosis by making radiotherapy more effective.

The 20 latest publications

Title Authors Publication date Source
CANTO-RT: One of the Largest Prospective Multicenter Cohort of Early Breast Cancer Patients Treated with Radiotherapy including Full DICOM RT Data Sofia Rivera 02/01/23 Cancers
Cytofluorometric characterization of the myeloid compartment of irradiated mouse tumors Marine Gerbé De Thoré, Lydia Meziani, Eric Deutsch, Michele Mondini 01/01/23 Methods in Cell Biology
Radiotherapy as a means to increase the efficacy of T-cell therapy in solid tumors Pierre Antoine Laurent, Lydia Meziani, Eric Deutsch 01/01/23 OncoImmunology
Chronic intermittent hypoxia, a hallmark of obstructive sleep apnea, promotes 4T1 breast cancer development through endothelin-1 receptors Mélanie Minoves, Sylvain Kotzki, Emeline Lemarié, Sophie Bouyon, Brigitte Gonthier, Jean Louis Pépin, Anne Briançon-Marjollet, Diane Godin-Ribuot 12/01/22 Scientific Reports
Favorable safety profile of moderate hypofractionated over normofractionated radiotherapy in breast cancer patients: a multicentric prospective real-life data farming analysis Eric Deutsch, Sofia Rivera 12/01/22 Radiation Oncology
Immune checkpoint-targeted antibodies: a room for dose and schedule optimization? Christophe Maritaz, S. Broutin, A. Paci 12/01/22 Journal of Hematology and Oncology
COMBING: Clustering in Oncology for Mathematical and Biological Identification of Novel Gene Signatures Enzo Battistella, Roger Sun, Theo Estienne, Marvin Lerousseau, Sergey Nikolaev, Emilie Alvarez Andres, Alexandre Carré, Stephane Niyoteka, Charlotte Robert, Eric Deutsch 11/01/22 IEEE/ACM Transactions on Computational Biology and Bioinformatics
Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation Giuseppe Arena, Eric Deutsch 10/31/22 Frontiers in Oncology
Radiomics to evaluate interlesion heterogeneity and to predict lesion response and patient outcomes using a validated signature of CD8 cells in advanced melanoma patients treated with anti-PD1 immunotherapy Roger Sun, Marvin Lerousseau, Jade Briend-Diop, Théophraste Henry, Alexandre Carré, Adrien Laville, Anthony Hamaoui, Pierre Antoine Laurent, Angela Rouyar, Charlotte Robert, Eric Deutsch 10/28/22 Journal for ImmunoTherapy of Cancer
Immune-related arthritis following pelvic radiation therapy in a patient with lung cancer receiving long-term immune checkpoint blocker treatment: Case report Eric Deutsch, A. Levy 10/24/22 Frontiers in Immunology
Immuno-radiotherapy: A review of the rationale, recent clinical developments and future prospects Eric Deutsch 10/01/22 Cancer/Radiotherapie
Practice changing clinical trials in radiation oncology in 2022 Sofia Rivera 10/01/22 Cancer/Radiotherapie
Apport et méthodologies innovantes des essais de phase I en oncologie thoracique : des phases 1 aux essais BASKET/plateforme Christophe Massard 10/01/22 Revue des Maladies Respiratoires Actualites
Radiotherapy-Related Dose and Irradiated Volume Effects on Breast Cancer Risk Among Hodgkin Lymphoma Survivors Cristina Veres, Ibrahima Diallo 09/01/22 Journal of the National Cancer Institute
Imaging approaches and radiomics: toward a new era of ultraprecision radioimmunotherapy? Eric Deutsch 07/01/22 Journal for ImmunoTherapy of Cancer
Two New Potential Therapeutic Approaches in Radiation Cystitis Derived from Mesenchymal Stem Cells: Extracellular Vesicles and Conditioned Medium Cyrus Chargari 07/01/22 Biology
Establishing a benchmark of diversity, equity, inclusion and workforce engagement in radiation oncology in Europe – An ESTRO collaborative project Anne Gasnier 06/01/22 Radiotherapy and Oncology
PD-1 iNhibitor and chemotherapy with concurrent IRradiation at VAried tumor sites in advanced Non-small cell lung cAncer: the Prospective Randomized Phase 3 NIRVANA-Lung Trial A. Levy 05/01/22 Clinical Lung Cancer
The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals Eric Deutsch 04/01/22 Cancer Discovery
How to Improve SBRT Outcomes in NSCLC: From Pre-Clinical Modeling to Successful Clinical Translation Marina Milic, Michele Mondini, Eric Deutsch 04/01/22 Cancers

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)