Interactions Cellules souches-niches: physiologie, tumeurs et réparation tissulaire (SToRM)

Laboratory presentation

The team develops projects in the areas of hematology, vascular biology, renal biology and tissue repair, studying the interactions between stem cells respective tissues and their microenvironments. Research programs include basic research approaches as well as their medical applications. Clinical studies focus on cell therapy for tissue repair and immuno-regulation of transplantation. The mutual interactions between tumor stem cells (leukemia and renal tumor) and their niches (bone marrow and renal tissue) are also studied.

The 19 latest publications

Title Authors Publication date Source
Producing vesicle-free cell culture additive for human cells extracellular vesicles manufacturing Bileyle Lorenzini, Juliette Peltzer, Sylvie Goulinet, Bastien Rival, Georges Uzan, Sébastien Banzet, Philippe Mauduit 03/01/23 Journal of Controlled Release
Leptospira interrogans Prevents Macrophage Cell Death and Pyroptotic IL-1b Release through Its Atypical Lipopolysaccharide Ahmed Outlioua 02/15/23 Journal of Immunology
The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes Hans Kristian Lorenzo 02/01/23 International Journal of Molecular Sciences
Research and Therapeutic Approaches in Stem Cell Genome Editing by CRISPR Toolkit Sara Shamdani, Georges Uzan, Sina Naserian 02/01/23 Molecules
Weighted correlation network analysis revealed novel long non-coding RNAs for colorectal cancer Sara Shamdani, Georges Uzan, Sina Naserian 12/01/22 Scientific Reports
Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor Mahsa Nouri Barkestani, Sina Naserian, Sara Shamdani 12/01/22 Scientific Reports
Induction temperature impacts the structure of recombinant HuGM-CSF inclusion bodies in thermoinducible E. coli Angélica B. Vargas-Castillo 09/01/22 Electronic Journal of Biotechnology
Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1 Ikram Hammi, Damien Arnoult 08/04/22 Molecular Cell
Principles and Applications of CRISPR Toolkit in Virus Manipulation, Diagnosis, and Virus-Host Interactions Georges Uzan, Sina Naserian 03/01/22 Cells
Generation of Hybrid Extracellular Vesicles by Fusion with Functionalized Liposomes Max Piffoux 01/01/22 Methods in molecular biology (Clifton, N.J.)
Enhanced High Mmutation Rrate and Nnatural Sselection to Pproduce Aattenuated Vviral Vvaccine with CRISPR Ttoolkit in RNA Vviruses especially SARS-CoV-2 Sina Naserian 01/01/22 Infection, Genetics and Evolution
Innate immunity: Trained immunity and innate allorecognition against the allograft Sara Shamdani, Sina Naserian 01/01/22 International Reviews of Immunology
Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1 Damien Arnoult 01/01/22 Autophagy
Development of extracellular vesicle-based medicinal products: A position paper of the group “Extracellular Vesicle translatiOn to clinicaL perspectiVEs – EVOLVE France” Max Piffoux, Philippe Mauduit, Christophe Martinaud, Clotilde Aussel, Marianne Dedier, Marina Trouillas, Juliette Peltzer, Sébastien Banzet 12/01/21 Advanced Drug Delivery Reviews
TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application Mahsa Nouri Barkestani, Sara Shamdani, Mazdak Afshar Bakshloo, Nassim Arouche, Georges Uzan, Sina Naserian 12/01/21 Cell Communication and Signaling
Human fetal liver MSCs are more effective than adult bone marrow MSCs for their immunosuppressive, immunomodulatory, and Foxp3<sup>+</sup> T reg induction capacity Yi Yu, Alejandra Vargas-Valderrama, Georges Uzan, Sina Naserian, Estelle Oberlin 12/01/21 Stem Cell Research and Therapy
Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers Mohamed Essameldin Abdelgawad, Georges Uzan, Sina Naserian 12/01/21 Stem Cell Research and Therapy
DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability Maria Teresa Mitjavila-Garcia 11/02/21 EMBO Journal
Engineering and loading therapeutic extracellular vesicles for clinical translation: A data reporting frame for comparability Max Piffoux 11/01/21 Advanced Drug Delivery Reviews

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)