Interactions Cellules souches-niches: physiologie, tumeurs et réparation tissulaire (SToRM)

Présentation du laboratoire

L'unité Interactions cellules souches-niches : physiologie, tumeurs et réparation tissulaire développe des projets dans les domaines de l'hématologie, de la biologie vasculaire, de la biologie rénale et de la réparation tissulaire, en étudiant des interactions mutuelles entre les cellules souches des tissus respectifs et leurs micro-environnements (niches). Les programmes de recherche incluent les approches de recherche fondamentale ainsi que leurs applications médicales. Les études cliniques sont centrées sur la thérapie cellulaire pour la réparation tissulaire et l'immuno-régulation de la transplantation. Les interactions mutuelles entre cellules souches tumorales (leucémie et tumeur rénale) et leurs niches (moelle osseuse et tissu rénal) sont également étudiées.

Les 19 dernières publications

Titre Auteurs Date de publication Source
Producing vesicle-free cell culture additive for human cells extracellular vesicles manufacturing Bileyle Lorenzini, Juliette Peltzer, Sylvie Goulinet, Bastien Rival, Georges Uzan, Sébastien Banzet, Philippe Mauduit 01/03/2023 Journal of Controlled Release
Leptospira interrogans Prevents Macrophage Cell Death and Pyroptotic IL-1b Release through Its Atypical Lipopolysaccharide Ahmed Outlioua 15/02/2023 Journal of Immunology
The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes Hans Kristian Lorenzo 01/02/2023 International Journal of Molecular Sciences
Research and Therapeutic Approaches in Stem Cell Genome Editing by CRISPR Toolkit Sara Shamdani, Georges Uzan, Sina Naserian 01/02/2023 Molecules
Weighted correlation network analysis revealed novel long non-coding RNAs for colorectal cancer Sara Shamdani, Georges Uzan, Sina Naserian 01/12/2022 Scientific Reports
Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor Mahsa Nouri Barkestani, Sina Naserian, Sara Shamdani 01/12/2022 Scientific Reports
Induction temperature impacts the structure of recombinant HuGM-CSF inclusion bodies in thermoinducible E. coli Angélica B. Vargas-Castillo 01/09/2022 Electronic Journal of Biotechnology
Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1 Ikram Hammi, Damien Arnoult 04/08/2022 Molecular Cell
Principles and Applications of CRISPR Toolkit in Virus Manipulation, Diagnosis, and Virus-Host Interactions Georges Uzan, Sina Naserian 01/03/2022 Cells
Generation of Hybrid Extracellular Vesicles by Fusion with Functionalized Liposomes Max Piffoux 01/01/2022 Methods in molecular biology (Clifton, N.J.)
Enhanced High Mmutation Rrate and Nnatural Sselection to Pproduce Aattenuated Vviral Vvaccine with CRISPR Ttoolkit in RNA Vviruses especially SARS-CoV-2 Sina Naserian 01/01/2022 Infection, Genetics and Evolution
Innate immunity: Trained immunity and innate allorecognition against the allograft Sara Shamdani, Sina Naserian 01/01/2022 International Reviews of Immunology
Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1 Damien Arnoult 01/01/2022 Autophagy
Development of extracellular vesicle-based medicinal products: A position paper of the group “Extracellular Vesicle translatiOn to clinicaL perspectiVEs – EVOLVE France” Max Piffoux, Philippe Mauduit, Christophe Martinaud, Clotilde Aussel, Marianne Dedier, Marina Trouillas, Juliette Peltzer, Sébastien Banzet 01/12/2021 Advanced Drug Delivery Reviews
TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application Mahsa Nouri Barkestani, Sara Shamdani, Mazdak Afshar Bakshloo, Nassim Arouche, Georges Uzan, Sina Naserian 01/12/2021 Cell Communication and Signaling
Human fetal liver MSCs are more effective than adult bone marrow MSCs for their immunosuppressive, immunomodulatory, and Foxp3<sup>+</sup> T reg induction capacity Yi Yu, Alejandra Vargas-Valderrama, Georges Uzan, Sina Naserian, Estelle Oberlin 01/12/2021 Stem Cell Research and Therapy
Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers Mohamed Essameldin Abdelgawad, Georges Uzan, Sina Naserian 01/12/2021 Stem Cell Research and Therapy
DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability Maria Teresa Mitjavila-Garcia 02/11/2021 EMBO Journal
Engineering and loading therapeutic extracellular vesicles for clinical translation: A data reporting frame for comparability Max Piffoux 01/11/2021 Advanced Drug Delivery Reviews

Nombre de publications du laboratoire par domaine scientifique (2016-2021)

Chaque publication du laboratoire peut être rangée dans une ou plusieurs disciplines scientifiques : la figure ci-dessus présente le nombre de publications du laboratoire pour chaque discipline de la classification ASJC (Elsevier)