Infection et inflammation (2I)

Laboratory presentation

The research laboratory for infection and chronic inflammation (2I) works on chronic inflammation, the immune system, the neuroendocrine response to sepsis or the pathophysiology and diagnosis of microbial infections. Research focuses more particularly on the first axis of rapidly growing mycobacteria infections in a context of respiratory disease (especially in patients with cystic fibrosis). The second line of research concerns coagulase-negative staphylococci and prosthetic infections. Finally, the last line of research concerns infections due to respiratory syncytial virus (RSV).

The 20 latest publications

Title Authors Publication date Source
Tracheostomy in ventilator-dependent patients with slowly progressive neuromuscular disease Djillali Annane 05/01/23 The Lancet Respiratory Medicine
Indoxyl sulfate impairs erythropoiesis at BFU-E stage in chronic kidney disease Islam Amine Larabi, Jean Claude Alvarez 04/01/23 Cellular Signalling
Noninvasive Vagus Nerve Stimulation: A New Therapeutic Approach for Pharmacoresistant Restless Legs Syndrome Guillaume Bao, Marine Zagdoun, Eric Azabou 04/01/23 Neuromodulation
The various inhaled corticoids. What are the respective advantages? E. Bardin, Stanislas Grassin-Delyle 04/01/23 Revue Francaise d'Allergologie
Metoclopramide Intoxication Through Breast Milk: Relevance of Blood and Hair Analyses Marie Bellouard, Jean Claude Alvarez 03/01/23 Indian Journal of Pediatrics
Forensic pre-hospital deaths related to fentanyl and its analogues in the Paris area: Data from the Île-de-France Toxic Death Surveillance System (DCTOX-IdF) Jean Claude Alvarez 03/01/23 Toxicologie Analytique et Clinique
Oligonucleotide Enhancing Compound Increases Tricyclo-DNA Mediated Exon-Skipping Efficacy in the Mdx Mouse Model Arnaud Mansart 03/01/23 Cells
Interleukin 27 is a novel cytokine with anti-inflammatory effects against spondyloarthritis through the suppression of Th17 responses Quentin Jouhault, Bilade Cherqaoui, Aude Jobart-Malfait, Simon Glatigny, Marc Lauraine, Audrey Hulot, Guillaume Morelle, Benjamin Hagege, Kétia Ermoza, Gilles Chiocchia, Maxime Breban, Luiza M. Araujo 02/02/23 Frontiers in Immunology
Paradoxical Effects of Endoplasmic Reticulum Aminopeptidase 1 Deficiency on HLA–B27 and Its Role as an Epistatic Modifier in Experimental Spondyloarthritis Maxime Breban 02/01/23 Arthritis and Rheumatology
Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: Multicenter observational study across 149 European Intensive Care Units Nicholas Heming 02/01/23 Anaesthesia, Critical Care & Pain Medicine
Extracellular traps formation following cervical spinal cord injury Camille H. Bourcier, Laila Emam, Adeline Gasser, Simon Glatigny, Arnaud Mansart 02/01/23 European Journal of Neuroscience
Correlation between Saliva Levels and Serum Levels of Free Uremic Toxins in Healthy Volunteers Elodie Lamy 02/01/23 Toxins
Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial Jean Claude Alvarez 01/09/23 Critical Care
Both Disease Activity and HLA–B27 Status Are Associated With Gut Microbiome Dysbiosis in Spondyloarthritis Patients Maxime Breban 01/01/23 Arthritis and Rheumatology
Target Analysis of Designer Benzodiazepines in Blood and Urine Islam Amine Larabi, Jean Claude Alvarez 01/01/23 Methods in Pharmacology and Toxicology
Efficacy of ceftazidime-avibactam in various combinations for the treatment of experimental osteomyelitis due to Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae Benjamin Davido, Anne Claude Crémieux, Laure Gatin, Azzam Saleh-Mghir 01/01/23 International Journal of Antimicrobial Agents
Management of the end of life in the emergency department: evaluation of a dedicated training course on emergency department practices at the CHU Ambroise Paré Sébastien Beaune 01/01/23 Soins. Gerontologie
Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3) Virginie Maxime 01/01/23 The Lancet Respiratory Medicine
Ribonucleoprotein transport in Negative Strand RNA viruses Cédric Diot, Gina Cosentino, Marie Anne Rameix-Welti 01/01/23 Biology of the Cell
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders Félicie Costantino, Simon Glatigny, Maxime Breban 01/01/23 Annals of the Rheumatic Diseases

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)