Biomarqueurs en cancérologie et onco-hématologie (BECCOH)

Laboratory presentation

The research activities of the BECCOH laboratory concern clinical trials and the development of biomarkers, for patients with cutaneous, digestive or pulmonary cancers, or histocytoses. The laboratory's teams aim for strong cross-sections, particularly around the development and validation of predictive and prognostic biomarkers allowing an ever increasing specification of the therapeutic management of patients. The BECCOH laboratory has a histological and molecular pathology platform for the study of neoplasia, and is backed by a center of biological resources (CRB) certified by AFNOR to NF96-900 standard.

The 20 latest publications

Title Authors Publication date Source
Nutritional Status of Vegetarian Patients Before and After Bariatric Surgery: a Monocentric Retrospective Observational Case–Control Study Mirella Hage, Ramona Zaharia, Séverine Coursault, Sandy Wilson, Elodie Gabali, Loïc Foussier, Marie Laure Raffin-Sanson, Marion Bretault 05/01/23 Obesity Surgery
Trop-2 is a ubiquitous and promising target in pancreatic adenocarcinoma Jean François Emile 04/01/23 Clinics and Research in Hepatology and Gastroenterology
Impact of systemic therapies in metastatic melanoma of unknown primary: A study from MELBASE, a French multicentric prospective cohort Philippe Saiag 04/01/23 Journal of the American Academy of Dermatology
Epidural lipomatosis in Cushing's syndrome causing regressive paraplegia Marie Laure Raffin-Sanson 02/01/23 Annales d'Endocrinologie
Serum vascular endothelial growth factor is associated with cardiovascular involvement and response to therapy in Erdheim-Chester disease Jean François Emile 02/01/23 Haematologica
OCT2 expression in histiocytoses Irena Antonia Ungureanu, Zofia Hélias-Rodzewicz, Jean Donadieu, Jean François Emile 01/01/23 Virchows Archiv
PU.1 is a useful nuclear marker to distinguish between histiocytosis and histiocyte-rich tumours Irena Antonia Ungureanu, Jean Donadieu, Jean François Emile 01/01/23 Histopathology
A nationwide French cohort study on 3154 patients with atopic dermatitis and psoriasis to assess patients' perception of dermatology residents A. Faugeroux, Romain Salle, Charbel Skayem 01/01/23 Journal of the European Academy of Dermatology and Venereology
Atopic dermatitis: A nationwide study on healthcare pathways and patient satisfaction of disease management in France Charbel Skayem, Romain Salle 01/01/23 Journal of the European Academy of Dermatology and Venereology
Abdominal Extrarenal Involvement in Erdheim-Chester Disease in a Cohort of 304 Patients Jean François Emile 12/15/22 JAMA oncology
Is rare cancer care organized at national health system level? Multiple case study in six EU countries Jean Francois Emile 11/29/22 European Journal of Public Health
Gene expression profile of high PD-L1 non-small cell lung cancers refractory to pembrolizumab Paul Takam Kamga, Marie Mayenga, Adrien Costantini, Catherine Julié, Jean François Emile, Etienne Giroux-Leprieur 11/01/22 Cancer Immunology, Immunotherapy
An open label, non-randomised, phase IIIb study of trametinib in combination with dabrafenib in patients with unresectable (stage III) or distant metastatic (stage IV) BRAF V600-mutant melanoma: A subgroup analysis of patients with brain metastases Philippe Saiag 11/01/22 European Journal of Cancer
Infections virales chroniques (hépatites, VIH) et impact sur le choix thérapeutique Etienne Giroux-Leprieur 10/01/22 Revue des Maladies Respiratoires Actualites
Erdheim–Chester disease long-bone osteosclerosis can be reproduced with a xenografted mouse model and its pathogenesis may involve dysregulation of bone metabolism key cytokines Jean François Emile 10/01/22 British Journal of Haematology
Formalin-fixed tissue Mohs surgery (slow Mohs) for trichoblastic carcinoma B. Bonsang, U. Zimmermann, Philippe Saiag, E. Funck-Brentano 10/01/22 Journal of the European Academy of Dermatology and Venereology
Safeness of Simultaneous Colonic Resection and Hepatic Radiofrequency Ablation M. Hajjam 10/01/22 Journal of the Society of Laparoendoscopic Surgeons
Combined nivolumab and ipilimumab in non-resectable Merkel cell carcinoma Philippe Saiag, A. Blom 09/24/22 The Lancet
Efficacy of Large Use of Combined Hypofractionated Radiotherapy in a Cohort of Anti-PD-1 Monotherapy-Treated Melanoma Patients Philippe Saiag, Rafaele Molinier, A. Roger, A. Blom, Christine Longvert, E. Funck-Brentano 09/01/22 Cancers
Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline – Update 2022 A. Blom, Philippe Saiag 08/01/22 European Journal of Cancer

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)