Deep tech and health start-up creation: Université Paris-Saclay ranked first in France and thirteenth in Europe
A recent report entitled The European Spinouts Report, published by Dealroom.co, examines the role played by university spin-offs in the European technology ecosystem and sheds new light on the role played by Université Paris-Saclay, its members and partners in the creation of innovative companies. The University is ranked first in France and thirteenth in Europe among universities that create start-ups in the fields of deep tech and health.
A new ranking confirms the leading role played by Université Paris-Saclay in the creation of innovative companies. After taking first place in the recent 2025 ranking of French higher education and research institutions most dynamic in deep tech entrepreneurship, compiled by Bpifrance's Deep Tech Observatory, the University now tops The European Spinouts Report's ranking of French universities creating start-ups in the fields of deep tech and health. The University also ranks 13th in the European rankings.
Further proof of the innovation potential and economic impact of the University and its partners
Published on 20 November 2025 by Dealroom.co, a provider of access to a global database and monitoring of European start-ups and innovation ecosystems, The European Spinouts Report reveals the role played by university spin-offs in the European technology ecosystem: job creation, fundraising, technological and industrial sovereignty. The report highlights the role of Paris-Saclay University, based on analysis carried out by IncubAlliance using Dealroom.co tools. This work is part of the University Innovation Cluster (PUI) Innovation Alliance Université Paris-Saclay*.
These positive results confirm the dynamism and power of the PUI Innovation Alliance Université Paris-Saclay in terms of creating deep tech start-ups. This consortium stands out in particular for its ability to offer each project – and its leader – a continuum of innovation based on entrepreneurship training, incubation and acceleration programmes, and pre-incubation and incubation facilities at the institutions that make up the PUI. These actions are further strengthened by growing links with investment funds and banks to facilitate the financing of innovative companies.
The dynamism and capacity for innovation in health of the consortium's founders and partners were particularly showcased at the recent RDV innovation en santé (Health Innovation Meeting), which took place on 19 November 2025 in Guyancourt. This field, which accounts for 40% of the research carried out in the laboratories, includes topics of major societal interest such as oncology, infectious diseases, rare diseases, central nervous system diseases, cardiovascular and pulmonary diseases, inflammatory and autoimmune diseases, and AI for health. The “health innovation panorama” produced by SATT Paris-Saclay and presented at this event can be downloaded here.
Health is also at the heart of the European University Alliance for Global Health (EUGLOH), which brings together nine research-intensive universities and is coordinated by Université Paris-Saclay.
* The University Innovation Cluster (PUI) Innovation Alliance Université Paris-Saclay brings together thirteen founding members, including Université Paris-Saclay, Université d'Évry, Université de Versailles - Saint-Quentin-en-Yvelines (UVSQ), AgroParisTech, CentraleSupélec, ENS Paris-Saclay, Institut d'Optique Graduate School, CNRS, INRAE, Inria, Inserm, IncubAlliance, SATT Paris-Saclay, and fifteen partners including CEA Paris-Saclay, Onera, Gustave Roussy, Genopole, the SystemX Institute for Technological Research, the Vedecom Institute for Energy Transition, the Paris-Saclay Urban Community, the Saint-Quentin-en-Yvelines Urban Community, the Grand Paris Sud Urban Community, the Vallée scientifique de la Bièvre Association, the Grand Orly Seine Bièvre Public Territorial Establishment, Systematic, Medicen, French Tech Paris-Saclay, the Paris-Saclay Public Development Authority, and funded by the French government as part of France 2030.