Researcher portraits, Research
Jacqueline Cherfils: from molecular switches to drugs
… of Biology and Applied Pharmacology (LBPA - Univ. Paris-Saclay, CNRS, ENS Paris-Saclay) , where she heads up … inactive (OFF) to the active (ON) state , and shortly afterwards the first structure of a GTPase-activating protein. … way . "Our GTPases need activators to which they bind in order to become active. However, instead of preventing this …
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