Modèles de cellules souches malignes et thérapeutiques (ONCOSTEM)

Laboratory presentation

The team brings together 3 independent research units to generate synergistic interactions in the field of malignant and therapeutic stem cells. In this configuration, Unit 935 associates a team with expertise in adult and embryonic stem cell biology with two teams working on membrane compartmentalization and chronobiology / chronotherapy. This association is expected to open new fields of research on development and differentiation and promote technology transfer. These teams are in close contact with a 4th team coordinating a national transfer technology network called INGESTEM dedicated to strategies for reprogramming adult cells into induced pluripotent stem cells (iPS).

The 20 latest publications

Title Authors Publication date Source
mTOR Inhibition Impairs the Activation and Function of Belatacept-Resistant CD4<sup>+</sup>CD57<sup>+</sup> T Cells In Vivo and In Vitro Jérôme Le Pavec, Olaf Mercier, Elie Fadel 04/01/23 Pharmaceutics
From normal hematopoiesis to malignancies: Highlights from the 2021 Meeting of the Club Hematopoiesis and Oncogenesis Dominique Bluteau 03/01/23 Bulletin du Cancer
The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes Hans Kristian Lorenzo 02/01/23 International Journal of Molecular Sciences
Pharmacologic modulation of 5-fluorouracil by folinic acid and pyridoxine for treatment of patients with advanced breast carcinoma David Machover, Christophe Desterke, Claude Boucheix 12/01/22 Scientific Reports
Real-world therapeutic response and tyrosine kinase inhibitor discontinuation in chronic phase-chronic myeloid leukemia: data from the French observatory Ali G. Turhan 10/01/22 Annals of Hematology
Letter to the editor: Organ shortage and pediatric liver transplantation: David against Goliath… Vincent Karam 05/01/22 Hepatology
Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study Yuki Kitano, Daniel Pietrasz, Elena Fernandez-Sevilla, Nicolas Golse, Eric Vibert, Antonio Sa Cunha, Daniel Azoulay, Daniel Cherqui, R. Adam, Marc Antoine Allard 03/21/22 Transplant International
European Liver Transplant Registry: Donor and transplant surgery aspects of 16,641 liver transplantations in children Vincent Karam, R. Adam 03/01/22 Hepatology
The proliferation of belatacept-resistant T cells requires early IFNα pathway activation Christophe Desterke 02/01/22 American Journal of Transplantation
Pharmacologic modulation of 5-fluorouracil by folinic acid and high-dose pyridoxine for treatment of patients with digestive tract carcinomas David Machover, Christophe Desterke, Claude Boucheix 12/01/21 Scientific Reports
Is Response to Genotoxic Stress Similar in Populations of African and European Ancestry? A Study of Dose-Response After in vitro Irradiation Noufissa Oudrhiri, Annelise Bennaceur-Griscelli 11/11/21 Frontiers in Genetics
The Liver Retransplantation Risk Score: a prognostic model for survival after adult liver retransplantation R. Adam, Vincent Karam 10/01/21 Transplant International
Hepatic Arteriovenous Malformation: The Search for a PTEN Mutation! Maïté Lewin 08/01/21 Hepatology
Bmal1 knockdown leans epithelial–mesenchymal balance toward epithelial properties and decreases the chemoresistance of colon carcinoma cells Yuan Zhang, Christophe Desterke, Lucas Eduardo Botelho de Souza, Eva Hadadi, Hervé Acloque, Adlen Foudi, Yunhua Chang 05/02/21 International Journal of Molecular Sciences
Effects of circadian rhythm disorders on breast cancer progression Hervé Acloque 05/01/21 Medecine/sciences
Liver Transplantation for Acute Intermittent Porphyria R. Adam, Vincent Karam 04/01/21 Liver Transplantation
Molecular investigation of adequate sources of mesenchymal stem cells for cell therapy of COVID-19-associated organ failure Christophe Desterke, Franck Griscelli, Jusuf Imeri, Paul Marcoux, Thomas Lemonnier, Theodoros Latsis, Ali G. Turhan, Annelise Bennaceur-Griscelli 04/01/21 Stem cells translational medicine
Ideal Surgical Margin to Prevent Early Recurrence After Hepatic Resection for Hepatocellular Carcinoma Hidetoshi Nitta, Marc Antoine Allard, Mylène Sebagh, Nicolas Golse, Oriana Ciacio, Gabriella Pittau, Eric Vibert, Antonio Sa Cunha, Daniel Cherqui, Denis Castaing, Henri Bismuth, R. Adam 04/01/21 World Journal of Surgery
Analgesic Effects of Topical Amitriptyline in Patients With Chemotherapy-Induced Peripheral Neuropathy: Mechanistic Insights From Studies in Mice Céline Greco 04/01/21 Journal of Pain
Asarylaldehyde enhances osteogenic differentiation of human periodontal ligament stem cells through the ERK/p38 MAPK signaling pathway Jin Wook Hwang 03/19/21 Biochemical and Biophysical Research Communications

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)