Signalisation, radiobiologie et cancer (SRC)

Laboratory presentation

The ETIC unit is responsible for major discoveries in the field of developmental biology, particularly in the neural crest and melanocyte lineage, as well as in the pathophysiology of melanoma and retinoblastoma. It works to elucidate the cellular and molecular mechanisms of normal and tumor development of melanocytes with the dual objective of identifying therapeutic targets and leading to new treatments in melanomas associated or not with radiotherapies. In collaboration with clinicians at the Curie Institute, teams can work with samples of patients with melanoma. They also benefit from the numerous technical platforms of the Institut Curie as well as the Protontherapy site on the Orsay campus.

The 20 latest publications

Title Authors Publication date Source
Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification Olivier Ayrault 05/01/23 Acta Neuropathologica
Proton minibeam radiation therapy for treating metastases: A treatment plan study Ramon Ortiz, Y. Prezado 04/01/23 Medical Physics
Derivation and Use of Cell Lines from Mouse Models of Melanoma Zackie Aktary, Jeremy H. Raymond, Marie Pouteaux, Véronique Delmas, Valérie Petit, Lionel Larue 04/01/23 Journal of Investigative Dermatology
Development of CMOS dosimetry in proton minibeams for enhanced QA and primary standard absorbed dose calorimetry Ludovic De Marzi, Ramon Ortiz, Annalisa Patriarca, Y. Prezado 03/01/23 Journal of Instrumentation
Ion recombination correction factors and detector comparison in a very-high dose rate proton scanning beam A. M.M. Leite 02/01/23 Physica Medica
Evaluation of the Role of the Immune System Response After Minibeam Radiation Therapy Catherine Sebrie, Laurène Jourdain 02/01/23 International Journal of Radiation Oncology Biology Physics
Orthovoltage X-ray Minibeam Radiation Therapy for the Treatment of Ocular Tumours—An In Silico Evaluation Tim Schneider, Y. Prezado 02/01/23 Cancers
Radiation-induced immune response in novel radiotherapy approaches FLASH and spatially fractionated radiotherapies Annaig Bertho, Lorea Iturri, Y. Prezado 01/01/23 International Review of Cell and Molecular Biology
Double scattering and pencil beam scanning Monte Carlo workflows for proton therapy retrospective studies on radiation-induced toxicities A. M.M. Leite 01/01/23 Cancer/Radiotherapie
Proton FLASH Radiation Therapy and Immune Infiltration: Evaluation in an Orthotopic Glioma Rat Model Catherine Sebrie, Laurène Jourdain 01/01/23 International Journal of Radiation Oncology Biology Physics
Challenges in glioblastoma research: focus on the tumor microenvironment Giorgio Seano 01/01/23 Trends in Cancer
Characterization of Ultra-High-Dose Rate Electron Beams with ElectronFlash Linac Lilia Aggar, Marie Dutreix, V. Favaudon, Sophie Heinrich 01/01/23 Applied Sciences (Switzerland)
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation (Nature, (2022), 609, 7929, (1021-1028), 10.1038/s41586-022-05215-w) Audrey L. Mercier, Olivier Ayrault 12/15/22 Nature
Preclinical modeling of low energy X-rays radiological burn: Dosimetry study by monte carlo simulations and EPR spectroscopy Y. Prezado 12/08/22 Frontiers in Physiology
Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis Giorgio Seano 12/07/22 EMBO Molecular Medicine
Perspectives in linear accelerator for FLASH VHEE: Study of a compact C-band system V. Favaudon, Sophie Heinrich 12/01/22 Physica Medica
Mafa-dependent GABAergic activity promotes mouse neonatal apneas Laure Lecoin, Alexandra Garancher, Nathalie Rocques, Alain Eychène, Celio Pouponnot 12/01/22 Nature Communications
Computational complexity: An empirical view Maël Pégny 12/01/13 6th AISB Symposium on Computing and Philosophy: The Scandal of Computation - What is Computation? - AISB Convention 2013
Computational complexity: An empirical view Maël Pégny 12/01/13 6th AISB Symposium on Computing and Philosophy: The Scandal of Computation - What is Computation? - AISB Convention 2013
New Robotic System with Wristed Microinstruments Allows Precise Reconstructive Microsurgery: Preclinical Study Alberto Ballestín 11/01/22 Annals of Surgical Oncology

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)