Matériaux et santé (MS)

Laboratory presentation

The MS lab is a research unit from Université Paris Sud which mainly focuses on the aging of pharmaceutical materials and drugs. It does so via 2 main research axis: (i) plastic materials used in pharmaceutical products and medical devices, and (ii) the drug modifications during pharmaceutical and environmental processes. The methodology for material aging study is based on a bulk and surface analysis of the material linked to the study of the interactions with biological media. This method allows the definition of the complex and dynamic relationships of the material with its environment (biological fluids, pharmaceutical formulations..) depending on the aging conditions. The drug stability studies are mainly conducted by liquid chromatography/mass spectrometry MS has major industrial and economic partnerships for and research.

The 20 latest publications

Title Authors Publication date Source
Comparative stability of intraocular lenses during 2–20 years of artificial aging, potential effects in terms of biocompatibility Lionel Tortolano 08/20/22 Journal of Applied Polymer Science
Development of Direct Grafting on Cyclic Olefin Copolymers to Improve Hydrophilicity by Using Bioactive Polymers E. Jubeli, A. Morocho, Najet Yagoubi 06/01/22 IRBM
Towards harmonization of solutions used for cystic fibrosis diagnosis by nasal potential difference measurements: A formulation approach with CHESS® software Eric Caudron, Patrice Prognon 01/01/22 Annales Pharmaceutiques Francaises
Bacteriological and mechanical impact of the Sterrad sterilization method on personalized 3D printed guides for mandibular reconstruction Lionel Tortolano 12/01/21 Scientific Reports
Phase Diagram Investigation and Thermodynamic Evaluation of the Thallium-Tellurium System M. C. Record, Yves Feutelais 11/09/21 International Journal of Materials Research
EBT3 Gafchromic® film as a new substrate for in vitro evaluation of sun protection factor Najet Yagoubi 05/01/21 European Journal of Dermatology
Are we correctly treating invasive candidiasis under continuous renal replacement therapy with echinocandins? Preliminary in vitro assessment Philippe Henri Secretan 02/01/21 Anaesthesia, Critical Care & Pain Medicine
Thermodynamic and Structural Powder Diffraction Studies of the Polymorphism of Florfenicol Bernard Legendre, Mehrez Sghaier 11/01/20 Journal of Pharmaceutical Sciences
Comparative analysis of docetaxel: physical and chemical characterisation of Taxotère® and generics Do Bernard, Solgadi Audrey 08/01/20 European Journal of Cancer
Stability of nivolumab in its original vials after opening and handing in normal saline bag for intravenous infusion Bernard Do 08/01/20 European Journal of Cancer
Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1<sup>MET</sup>/APR-246 Philippe Henri Secretan 01/01/20 Cell Death and Disease
The crucial role of macromolecular engineering, drug encapsulation and dilution on the thermoresponsiveness of UCST diblock copolymer nanoparticles used for hyperthermia Katia Manerlax, Najet Yagoubi 09/01/19 European Journal of Pharmaceutics and Biopharmaceutics
Effects of electron beam sterilization on polyethylene terephthalate: Physico-chemical modifications and formation of non-volatile organic extractables C. Aymes-Chodur, Najet Yagoubi 07/01/19 Annales Pharmaceutiques Francaises
Chemical and biological effects of low pressure N<inf>2</inf>-O<inf>2</inf> plasma setup on polymeric materials Omar Mrad 04/01/19 Journal of Polymer Engineering
Imatinib: Major photocatalytic degradation pathways in aqueous media and the relative toxicity of its transformation products Philippe Henri Secretan, Maher Karoui, Hassane Sadou-Yayé, Lionel Tortolano, Najet Yagoubi, Bernard Do 03/10/19 Science of the Total Environment
Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes Najet Yagoubi 01/01/19 Biochimica et Biophysica Acta - General Subjects
DinCH and ESBO actual migration from PVC infusion tubings used in an oncopediatric unit Lionel Tortolano, Houssem Matmati, Katia Manerlax, J. Saunier, Najet Yagoubi 09/20/18 Journal of Applied Polymer Science
Pemetrexed degradation by photocatalytic process: Kinetics, identification of transformation products and estimation of toxicity Philippe Henri Secretan, Maher Karoui, Hassane Sadou-Yayé, Lionel Tortolano, Najet Yagoubi, Bernard Do 05/15/18 Science of the Total Environment
Computerized pediatric oncology prescriptions review by pharmacist: A descriptive analysis and associated risk factors Lionel Tortolano 04/01/18 Pediatric Blood and Cancer
Reinvestigation of the paracetamol–caffeine, aspirin–caffeine, and paracetamol–aspirin phase equilibria diagrams Emma Dichi, Mehrez Sghaier 03/01/18 Journal of Thermal Analysis and Calorimetry

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)