Institut Galien Paris-Saclay (IGPS)

Laboratory presentation

The Institut Galien Paris Sud (IGPS) is a major international player in nanomedicine research. His goal is to develop nanotechnologies to deliver drugs to target cell populations and modulate their effects or for in vitro diagnostics and in vivo. The unit enjoys excellent international visibility thanks to its numerous publications and communications. His innovative work on nanomedicine attracts many collaborations, as evidenced by registered patents and industrial contracts. It is divided into three main poles (Physical Chemistry, Galenic Pharmaceuticals, Analytics) around which 7 teams with complementary skills are concentrated. It is a member of LabEx Lermit and NanoSaclay as well as the Paris-Sud Institute of Therapeutic Innovation (IPSIT). The IGPS has numerous scientific facilities grouped into common services for some throughout the site, which are available to everyone. They allow an optimal collaboration between the different teams of the unit and also attract external teams.

The 20 latest publications

Title Authors Publication date Source
On-line dual-stage enrichment via magneto-extraction and electrokinetic preconcentration: A new concept and instrumentation for capillary electrophoresis Ngoc Van Thanh Nguyen, Claire Smadja, Myriam Taverna, Thanh Duc Mai 05/15/23 Analytica Chimica Acta
Pickering emulsions stabilized with biodegradable nanoparticles for the co-encapsulation of two active pharmaceutical ingredients Mohamed Beladjine, Claire Albert, Ghozlene Mekhloufi, Claire Gueutin, Nicolas Tsapis, Florence Agnely, Nicolas Huang 04/25/23 International Journal of Pharmaceutics
Novel Strategy to Drive the Intracellular Uptake of Lipid Nanoparticles for Photodynamic Therapy Ali Makky 04/11/23 Angewandte Chemie - International Edition
RAFT-Mediated Emulsion Polymerization-Induced Self-Assembly for the Synthesis of Core-Degradable Waterborne Particles Maëlle Lages, Julien Nicolas 04/11/23 Angewandte Chemie - International Edition
Hyaluronan nanoplatelets exert an intrinsic anti-inflammatory activity in a rat model of bladder painful syndrome/interstitial cystitis Raul Diaz-Salmeron, Catherine Cailleau, Stéphanie Denis, G. Ponchel 04/01/23 Journal of Controlled Release
Resolution of MoS<inf>2</inf> Nanosheets-Induced Pulmonary Inflammation Driven by Nanoscale Intracellular Transformation and Extracellular-Vesicle Shuttles Benjamin Even, Hervé Hillaireau, E. Fattal 03/29/23 Advanced Materials
Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates Michel Roux 03/23/23 Journal of Physical Chemistry B
Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets Sameh Obeid 03/17/23 Journal of Visualized Experiments
Ice crystallization under cryogenic cooling in lipid membrane nanoconfined geometry: Time-resolved structural dynamics Angelina Angelova 03/15/23 Journal of Colloid and Interface Science
Self-Organization of Lipid-Porphyrin Conjugates at the Air/Water Interface Paul Cressey, Nada Ibrahim, Jana Alhoussein, Ali Makky 03/14/23 ChemPhysChem
Degradable polyisoprene by radical ring-opening polymerization and application to polymer prodrug nanoparticles Maëlle Lages, Théo Pesenti, Chen Zhu, Dao Le, Julie Mougin, Julien Nicolas 03/06/23 Chemical Science
Advances in extracellular vesicle analysis Lucile Alexandre, Myriam Taverna 03/01/23 Analytical and Bioanalytical Chemistry
Development and Characterization of Innovative Multidrug Nanoformulation for Cardiac Therapy Frédéric Gobeaux 03/01/23 Materials
Hierarchical superparamagnetic metal-organic framework nanovectors as anti-inflammatory nanomedicines Simona Mura 02/28/23 Journal of Materials Chemistry B
Amphiphilic Phosphorus Dendrons Associated with Anti-inflammatory siRNA Reduce Symptoms in Murine Collagen-Induced Arthritis Zhibo Yu, Nicolas Tsapis, Francois Fay, Catherine Cailleau, Nicolas Huang, Juliette Vergnaud, E. Fattal 02/13/23 Biomacromolecules
Increasing the Hydrophilicity of Cyclic Ketene Acetals Improves the Hydrolytic Degradation of Vinyl Copolymers and the Interaction of Glycopolymer Nanoparticles with Lectins Théo Pesenti, Seika Ishii, Julien Nicolas 02/13/23 Biomacromolecules
Degradable vinyl polymer particles by radical aqueous emulsion copolymerization of methyl methacrylate and 5,6-benzo-2-methylene-1,3-dioxepane Maëlle Lages, Julien Nicolas 02/13/23 Polymer Chemistry
Interaction of polyelectrolyte-shell cubosomes with serum albumin for triggering drug release in gastrointestinal cancer Angelina Angelova, Omar Mertins 02/03/23 Journal of Materials Chemistry B
Plasma membrane lipid bilayer is druggable: Selective delivery of gemcitabine-squalene nano-medicine to cancer cells Eleonore Coppens, Simona Mura, Patrick Couvreur 02/01/23 Biochimica et Biophysica Acta - Molecular Basis of Disease
In situ encapsulation of biologically active ingredients into polymer particles by polymerization in dispersed media Maëlle Lages, Julien Nicolas 02/01/23 Progress in Polymer Science

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)