Aller au contenu principal

Institut de biologie intégrative de la cellule (I2BC)

Laboratory presentation

The Institute of Integrative Cell Biology (I2BC) brings together numerous research teams working on all aspects of the cell, from cell constituents to cell interaction. The institute is divided into five research departments. The first department (B3S) uses many techniques to study biological assemblages at different scales. The Cell Biology department uses numerous eukaryotic models to study the physiological functions of cells. The Department of Genome Biology focuses on the study of genetic material. The Microbiology department is interested in different organisms, such as bacteria, archaea and their viruses, both for their specificities and as models to study biological mechanisms. Finally, the Virology department studies host-virus interactions and processes involved in viral infections.

The 19 latest publications

Title Authors Publication date Source
Elucidating dynamic anaerobe metabolism with HRMAS <sup>13</sup>C NMR and genome-scale modeling Johann Peltier 05/01/23 Nature Chemical Biology
Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize Armelle Vigouroux, Solange Moréra 05/01/23 Plant Journal
Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint Benjamin Cocom-Chan, Yosra Zarrouk, Christophe Le Clainche, Guy Tran Van Nhieu 04/25/23 Cell Reports
Dual-Uptake Mode of the Antibiotic Phazolicin Prevents Resistance Acquisition by Gram-Negative Bacteria Romain Jouan, Armelle Vigouroux, Joy Lachat, Fazal Haq, Tatiana Timchenko, Solange Moréra, P. Mergaert 04/25/23 mBio
Talin and kindlin cooperate to control the density of integrin clusters Julien Pernier, Marcelina Cardoso Dos Santos, Hemalatha Narassimprakash, Christophe Le Clainche 04/15/23 Journal of Cell Science
Using the Noncanonical Metallo-Amino Acid [Cu(II)(2,2′-Bipyridin-5-yl)]-alanine to Study the Structures of Proteins Leandro C. Tabares, Davis T. Daniel, José Luis Vázquez-Ibar, Sun Un 04/13/23 Journal of Physical Chemistry Letters
The FANCC-FANCE-FANCF complex is evolutionarily conserved and regulates meiotic recombination Raphaël Guerois 04/11/23 Nucleic Acids Research
Recipient UvrD helicase is involved in single- to double-stranded DNA conversion during conjugative plasmid transfer Minjia Shen, Sandra Daniel, Yoshiharu Yamaichi 04/11/23 Nucleic Acids Research
RNA:DNA hybrids from Okazaki fragments contribute to establish the Ku-mediated barrier to replication-fork degradation Armelle Gesnik, Paloma Fernández-Varela, Virginie Ropars, Jean Baptiste Charbonnier 04/06/23 Molecular Cell
Simulation of AOT reverse micelles with polyethylenimine in hexane Stéphane Abel 04/01/23 Colloid and Polymer Science
Mistimed origin licensing and activation stabilize common fragile sites under tight DNA-replication checkpoint activation Yan Jaszczyszyn, Claude Thermes 04/01/23 Nature Structural and Molecular Biology
Genome-wide measurement of DNA replication fork directionality and quantification of DNA replication initiation and termination with Okazaki fragment sequencing Nataliya Petryk 04/01/23 Nature Protocols
A journey in UPR modelling Ilaria Pontisso, Laurent Combettes 04/01/23 Biology of the Cell
Autocatalytic effect boosts the production of medium-chain hydrocarbons by fatty acid photodecarboxylase P. Samire, Bo Zhuang, P. Müller 03/31/23 Science advances
Role of the Protein Corona in the Colloidal Behavior of Microplastics Marion Schvartz, Florent Saudrais, Stéphane Chédin, Jocelyne Leroy, Olivier Taché, Serge Pin, Jean Philippe Renault 03/28/23 Langmuir
Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates Michel Roux 03/23/23 Journal of Physical Chemistry B
Understanding FRET in Upconversion Nanoparticle Nucleic Acid Biosensors Shashi Bhuckory, Jiajia Guo, Xue Qiu, Niko Hildebrandt 03/22/23 Nano Letters
Design, synthesis, and characterization of protein origami based on self-assembly of a brick and staple artificial protein pair Sébastien Viollet, Agathe Urvoas, Marie Valerio-Lepiniec, A. Mesneau, Inès Li De La Sierra-Gallay, Jessalyn Miller, Malika Ouldali, Philippe Minard 03/08/23 Proceedings of the National Academy of Sciences of the United States of America
Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling Gaëlle Lelandais 03/03/23 Journal of Proteome Research

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)