Aller au contenu principal

Ingénierie et Plateformes au Service de l'Innovation Thérapeutique (IPSIT)

Laboratory presentation

L’Institut Paris Saclay d’Innovation Thérapeutique (IPSIT) is a mixed unit of service (UMS) composed of 11 technological platforms. It plays a leading role in the development of the scientific projects of the associated units of Châtenay-Malabry, Clamart and Plessis Robinson sites whose common objectives are to identify new therapeutic targets. IPSIT is also at the service of private and public research laboratories from the Île-de-France Sud region.

The 9 latest publications

Title Authors Publication date Source
Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease Christine Péchoux 03/01/23 Molecular Metabolism
P2X7 purinergic receptor plays a critical role in maintaining T-cell homeostasis and preventing lupus pathogenesis Amine Mellouk, Tom Hutteau-Hamel, Hanaa Safya, Françoise Mercier-Nomé, Pierre Bobé 09/29/22 Frontiers in Immunology
Transcriptional profiling of β-2M<sup>−</sup>SPα-6<sup>+</sup>THY1<sup>+</sup> spermatogonial stem cells in human spermatogenesis Maelle Givelet, Virginie Firlej, Bruno Lassalle, Anne Sophie Gille, Clementine Lapoujade, Amandine Jarysta, Françoise Pflumio, Isabelle Allemand, Lydia Riou, Pierre Fouchet 04/12/22 Stem Cell Reports
Modulation of the Bile Acid Enterohepatic Cycle by Intestinal Microbiota Alleviates Alcohol Liver Disease Dragos Ciocan, Madeleine Spatz, Nicolas Trainel, Kévin Hardonnière, Cindy Hugot, Gabriel Perlemuter, Anne Marie Cassard 03/01/22 Cells
The unforeseen intracellular lifestyle of Enterococcus faecalis in hepatocytes Nicolas Trainel, Anne Marie Cassard 01/01/22 Gut Microbes
Abnormal migration behavior linked to Rac1 signaling contributes to primordial germ cell exhaustion in Fanconi anemia pathway-deficient Fancg-/- embryos Amandine Jarysta, Lydia Riou, Virginie Firlej, Clementine Lapoujade, Thierry Kortulewski, Vilma Barroca, Anne Sophie Gille, Isabelle Allemand, Pierre Fouchet 01/01/22 Human Molecular Genetics
The linoleic acid content of the stratum corneum of ichthyotic golden retriever dogs is reduced as compared to healthy dogs and a significant part is oxidized in both free and esterified forms Audrey Solgadi 12/01/21 Metabolites
Multi-tissue characterization of GILZ expression in dendritic cell subsets at steady state and in inflammatory contexts Molène Docq, Mathias Vétillard, Carmen Gallego, Agnieszka Jaracz-Ros, Françoise Mercier-Nomé, Françoise Bachelerie, Géraldine Schlecht-Louf 11/01/21 Cells
Rapid assessment of triacylglycerol fatty acyls composition by LC-APPI<sup>+</sup>-HRMS using monoacylglycerol like fragments intensities Audrey Solgadi 09/15/21 Analytica Chimica Acta

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)