Inflammation, microbiome, immunosurveillance (MI2)

Laboratory presentation

The Inflammation, Chimiokines and Immunopathology laboratory is interested in the pathophysiological mechanisms of the immune system and inflammation.Three teams are thematically sharing the work and are interested respectively in the immunological deregulation at the origin of the viral resistances , the influence of the intestinal microbiota on the liver resident macrophages, and finally the autoimmunities / immunodeficiencies. The presence of clinicians in the unit allows a translational approach research, as well as its membership in IPSIT and LabEx LERMIT leads to therapeutic innovations.

The 19 latest publications

Title Authors Publication date Source
Pectin in Metabolic Liver Disease Wanchao Hu, Anne Marie Cassard, Dragos Ciocan 01/01/23 Nutrients
Impact of sleeve gastrectomy on renal function in patients with morbid obesity: a 1-year prospective cohort study Amandine Lebrun, Sophie Prevot, Axel Balian, Sylvie Naveau, Gabriel Perlemuter, Cosmin Sebastian Voican 12/01/22 Langenbeck's Archives of Surgery
HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources Carmen Gallego, Géraldine Schlecht-Louf, Françoise Bachelerie 12/01/22 Nature Communications
Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19 Marine Peyneau, Vanessa Granger, Sylvie Chollet-Martin, L. de Chaisemartin 12/01/22 Scientific Reports
P2X7 purinergic receptor plays a critical role in maintaining T-cell homeostasis and preventing lupus pathogenesis Amine Mellouk, Tom Hutteau-Hamel, Hanaa Safya, Françoise Mercier-Nomé, Pierre Bobé 09/29/22 Frontiers in Immunology
Validation Study of a New Random-Access Chemiluminescence Immunoassay Analyzer i-TRACK10<sup>®</sup> to Monitor Infliximab and Adalimumab Serum trough Levels and Anti-Drug Antibodies Roman Krzysiek 09/01/22 International Journal of Molecular Sciences
Machine learning predicts response to TNF inhibitors in rheumatoid arthritis: results on the ESPOIR and ABIRISK cohorts Marc Pallardy 08/23/22 RMD Open
In the quest for treating alcohol liver disease Dragos Ciocan, Anne Marie Cassard 07/01/22 EBioMedicine
Hypercholesterolemia Negatively Regulates P2X7‐Induced Cellular Function in CD4<sup>+</sup> and CD8<sup>+</sup> T‐Cell Subsets from B6 Mice Fed a High‐Fat Diet Tom Hutteau-Hamel, Amine Mellouk, Nicolas Trainel, Anne Marie Cassard, Pierre Bobé 06/01/22 International Journal of Molecular Sciences
Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma Gabriel Perlemuter, Cosmin Sebastian Voican, Dragos Ciocan 04/15/22 International Journal of Cancer
Young GI angle: Challenges and opportunities as a trainee editor: The United European Gastroenterology journal experience Dragos Ciocan 04/01/22 United European Gastroenterology Journal
First Experience With Extracorporeal Cytokine Adsorption Therapy After Lung Transplantation Marine Peyneau, L. de Chaisemartin, Sylvie Chollet-Martin 03/21/22 Transplant International
Iatrogenic constipation in gastrointestinal surgery Cosmin Sebastian Voican, Gabriel Perlemuter 03/01/22 Journal of Visceral Surgery
Modulation of the Bile Acid Enterohepatic Cycle by Intestinal Microbiota Alleviates Alcohol Liver Disease Dragos Ciocan, Madeleine Spatz, Nicolas Trainel, Kévin Hardonnière, Cindy Hugot, Gabriel Perlemuter, Anne Marie Cassard 03/01/22 Cells
The unforeseen intracellular lifestyle of Enterococcus faecalis in hepatocytes Nicolas Trainel, Anne Marie Cassard 01/01/22 Gut Microbes
Investigation of inherited chromosomally integrated human herpesvirus-6a+ and-6b+ in a patient with ulipristal acetate-induced fulminant hepatic failure Claire Deback 01/01/22 Viruses
Specific microbiome profile in Takayasu’s arteritis and giant cell arteritis Dragos Ciocan, Gabriel Perlemuter 12/01/21 Scientific Reports
Eicosapentaenoic acid membrane incorporation stimulates ABCA1-mediated cholesterol efflux from human THP-1 macrophages Benoît Noël 11/01/21 Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Multi-tissue characterization of GILZ expression in dendritic cell subsets at steady state and in inflammatory contexts Molène Docq, Mathias Vétillard, Carmen Gallego, Agnieszka Jaracz-Ros, Françoise Mercier-Nomé, Françoise Bachelerie, Géraldine Schlecht-Louf 11/01/21 Cells

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)