M2 Toxicologie Humaine, Evaluation des Risques et Vigilance (THERV)

Master's degree
Specialisation Pharmaceutical Science
Full-time academic programmes
Professional training contract
Life-long learning
English
French

Multidisciplinary in nature, toxicology is a rare cross-disciplinary field that combines medicine, biology, chemistry, and environmental sciences. The diversity of the teaching units available to candidates during the M2THERV program provides them with excellent training as general toxicologists or more specialized toxicologists in regulatory toxicology.

A 3-week core program followed by one teaching unit per month

Information

Présentation

Skills

1. Establish the relationship between identifying the hazards associated with a product and the risks associated with its use.

2. Use scientific reasoning and experimental methods (toxicity assessment models) in the field of toxicology.

3. Communicate and argue the results of your research in writing and orally in both French and English.

4. Critically analyze scientific articles and regulatory reports in order to find relevant information.

5. Understand the essential elements of regulatory toxicology for health products and know how to self-train in this field.

6. Apply essential knowledge in health product vigilance, including regulatory aspects.

Objectives

Graduates with a master's degree in Toxicology are legally authorized to perform risk assessment functions in both the pharmaceutical and cosmetics industries. Consequently, they must have all the knowledge required in the field of toxicity mechanisms, toxicity assessment methods, and related regulations necessary to perform this function.

Career Opportunities

Career prospects

Après Master + Doctorat : chercheur ou enseignant-chercheur
Responsable formulation et innovation cosmétique
Responsable assurance qualité
Responsable de projets R&D
Chargé.e de recherche et innovation
Chef·fe de projet en biotechnologies, biothérapies ou innovation en santé
Chargé d'affaires réglementaires en santé

Fees and scholarships

The amounts may vary depending on the programme and your personal circumstances.

Calendar

Start of programme (indicative date)
04/09/2026
End of programme (indicative date)
09/07/2027
Admission

Capacity

Available Places

25

Target Audience and Entry Requirements

- Students who have completed a Master's 1 degree in SMPS or a related field (Biology, Biology-Health) at a university offering education comparable to that of Paris-Saclay University, in France or in European Union countries, after validation of specific prerequisite knowledge by the Master's 2 program director;

- Students who have studied health sciences (pharmacy, medicine, dentistry, veterinary medicine) in the European Union (and universities with agreements), having completed the fifth year of study or an equivalent to an M1 degree;

- Students with an engineering degree equivalent to an M1 degree;

- Be under 30 years of age to be eligible for an apprenticeship contract.

- Initial knowledge of toxicology, an academic level in the field and related fields (depending on the candidates' profile: biology, pharmacology, public health, etc.) and experience in the field of toxicology (research internships, in industry, in agencies) are required.

Application Period(s)

Inception Platform

From 02/02/2026 to 15/05/2026

Supporting documents

Compulsory supporting documents

Motivation letter.

All transcripts of the years / semesters validated since the high school diploma at the date of application.

Curriculum Vitae.

Detailed description and hourly volume of courses taken since the beginning of the university program.

describe in detail the Toxicology and Biology courses, with particular emphasis on the optional courses followed

Additional supporting documents

Pharmacy or engineer transcripts.

Certificate of English level.

Certificate of French (compulsory for non-French speakers).

Level B2 required

VAP file (obligatory for all persons requesting a valuation of the assets to enter the diploma).

Recommendation letters.

Supporting documents :
- Residence permit stating the country of residence of the first country
- Or receipt of request stating the country of first asylum
- Or document from the UNHCR granting refugee status
- Or receipt of refugee status request delivered in France
- Or residence permit stating the refugee status delivered in France
- Or document stating subsidiary protection in France or abroad
- Or document stating temporary protection in France or abroad.

Programme
Subjects ECTS Semester Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
V2 - Toxicologie Réglementaire 1 : définitions, principes et organisations 3 Semestre 1 20 5
V3 - Toxicologie Réglementaire 2 : expérimentation et tests 3 Semestre 1 20 5
V14 - Discussion avec jury sur projet et article 3 Semestre 1
V13 - Présentation projet et article 3 Semestre 1
M1 - Mécanisme d'action des toxiques 3 Semestre 1 22 3
V7 - Toxicologie cellulaire 3 Semestre 1 18 7
M2 - Pathologies non tumorales 3 Semestre 1 19 6
Subjects ECTS Semester Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
V2 - Toxicologie Réglementaire 1 : définitions, principes et organisations 3 Semestre 1 20 5
V3 - Toxicologie Réglementaire 2 : expérimentation et tests 3 Semestre 1 20 5
V1 - Toxicologie d'organes 3 Semestre 1 17 8
V9 - Anatomo-Pathologie 3 Semestre 1 16
V8 - Analyse de cas 3 Semestre 1 0 25
V6 - Toxicologie Analytique 3 Semestre 1 16 6
V5 - Immunotoxicologie 3 Semestre 1 18 7
V12 - Ingénierie tissulaire et toxicologie prédictive : Application aux dispositifs médicaux et cosmétiques 3 Semestre 1
V11 - Métabolisme et tranports des xénobiotiques 3 Semestre 1 16 6
V10 - Toxicologie Clinique 3 Semestre 1 25 0
S7 - Toxicologie réglementaire des produits chimiques 3 Semestre 1 30
S6 -  Ecotoxicologie 3 Semestre 1 30
S8 - Toxicologie de la reproduction 3 Semestre 1 30
V4 - Toxicologie Réglementaire 3 : les vigilances 3 Semestre 1 20
S9 - Toxicologie des aliments 3 Semestre 1 30
M3 - Cancérogénèse et pathologies tumorales 3 Semestre 1 19 6
UE libre S2 3 Semestre 2
Subjects ECTS Semester Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Stage 30 Semestre 2

Teaching Location(s)

ORSAY
PARIS 06

Contact

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