M2 Biotherapies : Tissue, Cell, Gene

Apply for the degree
  • Places available
    15
  • Language(s) of instruction
    English
    French
Présentation
Objectives

This study path is based on the science and health curriculum of year 1 in Biology-Health (M1). All teaching units are grouped together in year 1 and organised into platforms (lists of teaching units to choose from), classified into five major scientific fields. The platforms recommended in M1 are:
Genetics, Molecular and Cellular Biology
Physiology and Physiopathology
The goal of the typical study path is two-fold: give students from different undergraduate backgrounds a strong foundation in fundamental research, and to provide various openings to the professional world of health.
The aim of this specialisation is to impart skills that can be applied in the fields of biotherapies, which covers genotherapies (gene transfer, interventions on genes), replacement cytotherapies (manipulations of stem cells or differentiated cells), immunotherapy, certain innovative pharmacotherapies, and the use of biomaterials.

Location
CRETEIL
EVRY
BOBIGNY
Course Prerequisites

Master 1 level or equivalent with basics in cellular and molecular biology

Skills
  • Cite and evaluate specific tools and animal models used in biotherapies.

  • Build new therapies for the treatment of genetic diseases as well as different approaches to cell therapy.

  • Develop various immunotherapy methods.

  • Specify the specific characteristics of the pharmaceutical industry.

  • Analyse and interpret biotherapy data.

Post-graduate profile

After this Master's programme, successful students may either pursue a PhD or follow a professional career in research and development in pharmaceutical or biotechnology industry and acamedic laboratory. Students from the professional option often integrate an ARC (Attaché de Recherche Clinique) training course or join industry in a engineering position.

Career prospects

- Biotechnology, research and development in industry, academic research, scientific communication and popularisation, medicine, pharmacy, veterinary medicine.
- Research positions and clinical applications in the medical and surgical fields, positions in the pharmaceutical and veterinary fields that relate to the development and evaluation of biotherapy protocols.
- Positions related to medicine in the pharmaceutical industry, French or European health agencies, biotechnology industries.
- Senior executive positions in industry, biotechnology companies, regulatory agencies, research organisations

Collaboration(s)
Laboratories

Approches génétiques intégrées et découvertes thérapeutiques pour les maladies rares
Biologie du Développement et Reproduction
Biomarqueurs en cancérologie et onco-hématologie
Biomarqueurs prédictifs et nouvelles stratégies thérapeutiques en oncologie
Biomolécules : Conception, Isolement, Synthèse
Centre de Recherche en épidémiologie et Santé des populations
Centre de recherche en Immunologie des infections virales et des maladies autoimmunes - DRF/JACOB
Centre de Nanosciences et de Nanotechnologies
Centre National de Recherche en Génomique Humaine - DRF/JACOB
Département Médicaments et technologies pour la santé - DRF/JOLIOT
Genoscope - DRF/JACOB
Hématopoièse Normale et Pathologique
Immunologie des tumeurs et Immunothérapie
Infection et inflammation Chronique
Institut des Cellules souches pour le traitement et l'étude des maladies monogéniques
Institut des maladies émergentes et des thérapies nouvelles - DRF/JACOB
Institut Paris Saclay d'Innovation thérapeutique
Institute for Integrative Biology of the Cell - DRF/JOLIOT
Interactions Cellules souches-niches: physiologie, tumeurs et réparation tissulaire
Laboratoire des Maladies Neurodégénératives : mécanismes, thérapies, imagerie - DRF/JACOB/MIRCen.

Programme
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Presentation of Training Project-UEVE 2 10
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Scientific Watch and Communication 10 10
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
High Throughput Analysis and Gene Editing 4 10.5
Clinical Research in Biotherapies 4 30
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Scientific Watch and Communication (Pro) 7 10
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Specific Tools of Biotherapies 3 30
Animal Models 2 20
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Transfusion and Biotherapies 1.5 12
Regenerative Medicine 1.5 18
New Therapies for Genetic Diseases 2 13.5
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Immunotherapies for Immune Diseases 2 10
Antineoplasic Strategies 2 20
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Implementation of Industrial Strategy 4.5 30
Corporate Life 4.5 15
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Clinical Research in Biotherapies 4 30
Subjects ECTS Lecture directed study practical class Lecture/directed study Lecture/practical class directed study/practical class distance-learning course Project Supervised studies
Stage en laboratoire ou entreprise - P5 30
Modalités de candidatures
Application period
From 01/03/2021 to 05/07/2021
Compulsory supporting documents
  • Curriculum EU (description of the units of education followed) of the last two years.

  • Curriculum Vitae.

  • Motivation letter.

  • All transcripts of the years / semesters validated since the high school diploma at the date of application.

Additional supporting documents
Contact(s)
Course manager(s)
Christine Baldeschi - cbaldeschi@istem.fr
Admission