The scientific and medical communities of the GS LSH are mobilizing against COVID-19

Research Article published on 09 July 2020 , Updated on 21 April 2021

Two of the 20 research projects selected by the REACTing scientific council to fight against the Covid epidemic19  are led by GS LSH research teams around the following objectives:  

  • Establishment of an experimental SARS-CoV-2 infection model in cynomolgus monkeys. Principal investigator: Roger Le Grand (INSERM, CEA, University Paris-Saclay - National Biology Health Infrastructure IDMIT)
  • Development of a replicon for the Covid-19 coronavirus. Principal investigator: Jean-François Eléouët (INRAE), Molecular Virology and Immunology Unit

In addition, 4 projects led by GS LSH teams are funded under the Flash call COVID-19 launched by the ANR: -

  • AM-Cov-Path: Pathogenesis of SARS-Cov-2 infection in a non-human primate model: a model for treatment and prevention. Roger LE GRAND (UMR-S 1184 IMVA-HB, IDMIT, CEA Fontenay-aux-Roses) 
  • ICARE: Initial COVID-19-associated SARS-CoV-2 Cell Atlas and Response. Isabelle SCHWARTZ  (UMR 0892 - Molecular Virology and Immunology Unit - VIM, INRAe/UVSQ/UPSaclay – Jouy-en-Josas)
  • MacCOV: Functional reprogramming of macrophages: a therapeutic objective to be achieved in order to combat acute respiratory distress associated with SARS-CoV-2 infection? Jean-Luc PERFETTINI (UMR-S 1030 INSERM/UPSaclay/GustaveRoussy, Villejuif)
  • SARS2BlockEntry: Construction of nano-ligands to block the entry of SARS-CoV-2. Bernard DELMAS (UMR 0892 - Molecular Virology and Immunology Unit - VIM, INRAe/UVSQ/UPSaclay – Jouy-en-Josas) Gustave Roussy's teams are thus developing or participating in various studies, recently launched or about to be launched, in both clinical and translational research, including ONCOVID, SANcovPCR, ONCOVID-19, TERAVOLT, CORIMMUNO-19, GCO-Cancer COVID19.

For more information: https://www.gustaveroussy.fr/fr/la-Research-de-gustave-roussy-mobilisee…

The Institut d'Alembert (IA) of the ENS Paris-Saclay has just labeled two new projects oriented COVID-19. These projects, which aim to develop new methods to inhibit the entry of the virus into cells (treatment), or new methods to detect this virus (diagnosis), involve the School's biology (LBPA), chemistry (PPSM) and physics (LUMIN) laboratories, in collaboration with laboratories at the University of Paris-Saclay (LAMBE). 

ACTU PEOPLE "We're going to have to live with it for two years," says Yves Gaudin (Research Director, Institute for the INtegrative Biology of the Cell - I2BC, CNRS/CEA/University Paris-Saclay), member of the Scientific Council REACTing 2019-nCoV, future Deputy Director of Research of the GS LSH.

How do the Covid-19 tests work? Find the explanations of Clémence Richetta, lecturer at the Biology Department and researcher in virology at the Laboratory of Biology and Applied Pharmacology (LBPA) of the ENS Paris-Saclay.