[{"command":"insert","method":null,"selector":".course-modal-ajax-placeholder-968184","data":"\u003Cdiv class=\u0022container content-rte\u0022\u003E\n  \u003Cdiv class=\u0022row\u0022\u003E\n    \u003Cdiv class=\u0022box col-md-6 bg-primary text-white\u0022\u003E\n      \u003Ch2 class=\u0022h1 text-left\u0022\u003E  TU13 Therapies of cardiovascular dysregulations and beyond\n\u003C\/h2\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EECTS :\n          2\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ESemestre calendaire :\n          Semestre 1\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ED\u00e9tail du volume horaire\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ECours magistraux :\u003C\/span\u003E\n                                      \u003Cspan\u003E12\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                                                          \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003EProjet :\u003C\/span\u003E\n                                      \u003Cspan\u003E6\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ELangue d\u0026#039;enseignement\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EAnglais\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EEnseignement \u00e0 distance\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003Enon\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n    \u003Cdiv class=\u0022box col-md-6\u0022\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EPr\u00e9requis\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EBeing registered in the master D2HP, basis in cardiovascular physiology and some general basis of cardiovascular pathologies (acquired in D2HP TU3) : hypertension, ischemic diseases, heart failure\u003C\/p\u003E\n\u003Cp\u003Ebasis in pharmacology : affinity, activity, and selectivity of a pharmacological compound (acquired in D2HP TU11)\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EProgramme \/ plan \/ contenus\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003ELecture courses will typically follow the 1,5 format session ( 8 sessions)\u003C\/p\u003E\n\u003Cp\u003Ethe current approved therapies will be covered , highlighting the molecular targets and mechanisms responsible for efficacy and adverse effects. \u0026nbsp;\u003C\/p\u003E\n\u003Cp\u003Eexperts and researchers will present their research works on emerging therapeutic targets. They will introduce methodologies and models used in basic research\u0026nbsp;\u003C\/p\u003E\n\u003Cp\u003Esuch topics will include:\u003C\/p\u003E\n\u003Cp\u003Ecardiac metabolism\u003C\/p\u003E\n\u003Cp\u003Eintracellular calcium handling\u003C\/p\u003E\n\u003Cp\u003Epathways downstream to receptors to signalling molecules\u003C\/p\u003E\n\u003Cp\u003Evascular targets to treat thrombo inflammatory disorders\u003C\/p\u003E\n\u003Cp\u003Einnovative drug discovery emerging therapies based on biotechnologies\u003C\/p\u003E\n\u003Cp\u003Eintroduction to the clinical validation of the efficacy and safety of new pharmaceuticals will be also provided\u003C\/p\u003E\n\u003Cp\u003EPersonal and group will be encouraged to practically apply these esential notions to case studies (tutored project) . Much attention will be brought to current \u0022hot\u0022 topics in the field\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EObjectifs d\u0026#039;apprentissage\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003Eto identify the main pharmacological classes used to treat cardiovascular disorders : their targets, their mechanisms of action and their side effects\u003C\/p\u003E\n\u003Cp\u003Eto analyze a therapy globally , by assessing both efficacy and safety issues through fundamental and clinical approaches\u003C\/p\u003E\n\u003Cp\u003Eto discover the research concepts and opportunities afforded by emerging therapeutic targets and biomarkers in the field of cardiovascular research. Perspectives into some connected fields such as dyslipidemia, thrombo inflammation will also be proposed\u0026nbsp;\u003C\/p\u003E\n\u003Cp\u003Eto be able to consider how a scientific question may be addressed and answered by an experiment, using relevent models methodologies and analytical tools\u003C\/p\u003E\n\u003Cp\u003ETo critically analyze scientific data and results\u003C\/p\u003E\n\u003Cp\u003Eto extract the key messages of a scientific publication and communicate information in a synthetic and accurate manner\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EComp\u00e9tences\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003ETo identify the main cardiovascular pathologies with their respective known molecular mechanisms and therapy\u003C\/p\u003E\n\u003Cp\u003Eto critically analyze a novel therapeutic strategy from the angle of target, mechanism afficacy and safety.\u003C\/p\u003E\n\u003Cp\u003Eto analyze bibliographic material, by being able to understand cutting edge experimental methodologies data presentation and interpretation\u003C\/p\u003E\n\u003Cp\u003Erelational collaborative and communication skills (written and oral)\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EBibliographie\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EHerring et al , Introdcution to cardiovascular Physiology 6th edition CRC Press 2018\u003C\/p\u003E\n\u003Cp\u003EZipes et al : Braunwald\u0027s Heart Disease : A textbook of cardiovascular medicine, 11th edition Elsevier 2018\u003C\/p\u003E\n\u003Cp\u003ERand and Dale\u0027s Pharmacology 10th edition Elsevier 2023\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ENature de l\u0026#039;\u00e9valuation\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EEvaluation Continue non Int\u00e9grale\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n","settings":null}]