[{"command":"insert","method":null,"selector":".course-modal-ajax-placeholder-963954","data":"\u003Cdiv class=\u0022container content-rte\u0022\u003E\n \u003Cdiv class=\u0022row\u0022\u003E\n \u003Cdiv class=\u0022box col-md-6 bg-primary text-white\u0022\u003E\n \u003Ch2 class=\u0022h1 text-left\u0022\u003E UE Single cell and spatial multi-omics, high-throughput screening\n\u003C\/h2\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EECTS :\n 3\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ESemestre calendaire :\n Semester 1\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ED\u00e9tail du volume horaire\u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ECours magistraux :\u003C\/span\u003E\n \u003Cspan\u003E15\u003C\/span\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ETravaux dirig\u00e9s :\u003C\/span\u003E\n \u003Cspan\u003E7.5\u003C\/span\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ELangue d\u0026#039;enseignement\u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan\u003EAnglais\u003C\/span\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EEnseignement \u00e0 distance\u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan\u003Enon\u003C\/span\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022box col-md-6\u0022\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EProgramme \/ plan \/ contenus\u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan\u003E\u003Cp\u003EThis teaching unit will provide an overview of the breaking edge technologies allowing to :\u003C\/p\u003E\n\u003Cp\u003E- Study the complexity and heterogenerous nature of the samples at both genomic, epigenomic and transcriptional level, i.e. single-cell omic approaches, spatial transcriptomic, single-cell DNA barcoding, metagenomic, single-cell DNA barcoding approaches for lineage tracing, metagenomic.\u003C\/p\u003E\n\u003Cp\u003EIt will provide knowledge on advantage and limitations of the main single cell approaches, spatial-transcriptomic technologies\u003C\/p\u003E\n\u003Cp\u003E- Identify and develop new therapeutic targets (genome-wide RNAi, CrispR\/Cas9 knockout screens, drug screening)\u003C\/p\u003E\u003C\/span\u003E\n \u003C\/div\u003E\n \u003C\/div\u003E\n \u003Cdiv class=\u0022field-spacing\u0022\u003E\n \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EObjectifs d\u0026#039;apprentissage\u003C\/div\u003E\n \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n \u003Cspan\u003E\u003Cp\u003EThis course will provide an overview of genomic tools and strategy dedicated to address questions related to the description the cellular composition of complex tissue, definition of the cellular hierarchy of differentiation in both physiological and pathological condition, exploration of immunity dysregulation in disease context, identification of the cell of origin of the disease, study of disease cells interaction with their microenvironment, microbiome composition and variations in health and disease, finding disease cell vulnerabilities.\u003C\/p\u003E\n\u003Cp\u003EIt will help student to identify current challenges in the genomic field and opportunity to undress news scientific points.\u003C\/p\u003E\u003C\/span\u003E\n 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