MICrobiologie de l'ALImentation au Service de la Santé Humaine

Présentation du laboratoire

MICALIS développe des recherches novatrices dans le champ de la Microbiologie de l'Alimentation au service de la Santé. Les chercheurs de cet Institut unique en France travaillent sur l'étude des écosystèmes microbiens alimentaire et intestinal et les interactions avec l'hôte, l'émergence et le contrôle des microorganismes pathogènes opportunistes d'origine alimentaire ainsi que la biologie systémique et synthétique microbienne. L'institut abrite 5 plateformes technologiques : - animalerie axénique - microscopie et imagerie des microorganismes, analyse protéomique de Paris sud-ouest - ressources microbiennes-levures - démonstrateur préindustriel de métagénomique intestinal. Les travaux et brevets déposés sur l'amélioration de la production de levains alimentaires, la prévention du risque microbiologique dans la chaîne alimentaire et sur la production d'outils de diagnostic de pathologies humaines et des stratégies nutritionnelles et probiotiques permet à l'institut d'être un partenaire socio-économique actif (Probiox, Danone).

Les 20 dernières publications

Titre Auteurs Date de publication Source
Permissive Fatty Acid Incorporation Promotes Staphylococcal Adaptation to FASII Antibiotics in Host Environments Alexandra Gruss, Claire Morvan, Karine Gloux, ... 17/12/2019 Cell Reports
Fecal microbiome as determinant of the effect of diet on colorectal cancer risk: Comparison of meat-based versus pesco-vegetarian diets (the MeaTIc study) Philippe Gérard 09/12/2019 Trials
Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells Hervé M. Blottière, Nicolas Lapaque, Camille Martin-Gallausiaux, ... 01/12/2019 Scientific reports
Exon junction complex components Y14 and Mago still play a role in budding yeast Cécile Neuvéglise, Hugo Devillers, François Brunel, ... 01/12/2019 Scientific Reports
Alternative splicing events expand molecular diversity of camel CSN1S2 increasing its ability to generate potentially bioactive peptides Céline Henry 01/12/2019 Scientific Reports
The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus production and cytoprotective response Philippe Langella, Luis G. Bermúdez-Humarán, Florian Chain, ... 01/12/2019 Scientific Reports
Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors Jean Loup Faulon, Mathilde Koch, Amir Pandi 01/12/2019 Nature Communications
A microbiota-generated bile salt induces biofilm formation in Clostridium difficile Julien Deschamps, R. Briandet 01/12/2019 npj Biofilms and Microbiomes
Intestinal translocation of enterococci requires a threshold level of enterococcal overgrowth in the lumen Nicolas Lapaque, Lionel Rigottier-Gois, Pascale Serror, ... 01/12/2019 Scientific Reports
A Guide for Ex Vivo Handling and Storage of Stool Samples Intended for Fecal Microbiota Transplantation K. Le Roux, Patricia Lepage, Joel Dore, ... 01/12/2019 Scientific Reports
The commensal Escherichia coli CEC15 reinforces intestinal defences in gnotobiotic mice and is protective in a chronic colitis mouse model Muriel Thomas, Philippe Langella, Claire Cherbuy, ... 01/12/2019 Scientific Reports
Metabolic perceptrons for neural computing in biological systems Jean Loup Faulon, Manish Kushwaha, Mathilde Koch, ... 01/12/2019 Nature Communications
Iron deficiency and anemia in adolescent girls consuming predominantly plant-based diets in rural Ethiopia Muriel Thomas, Yohannes Seyoum 01/12/2019 Scientific Reports
Characterization and Whole Genome Sequencing of AR23, a Highly Toxic Bacillus thuringiensis Strain Isolated from Lebanese Soil Vincent Sanchis-Borja, Rafael Patiño-Navarrete 01/12/2019 Current Microbiology
Criteria to indicate kidney biopsy in type 2 diabetic patients with proteinuria: Survey among French nephrologists Jonathan Maurice Chemouny 01/12/2019 Nephrologie et Therapeutique
Characterization of the gen locus involved in β-1,6-oligosaccharide utilization by Enterococcus faecalis Josef Deutscher 01/12/2019 Molecular Microbiology
Stool for fecal microbiota transplantation should be classified as a transplant product and not as a drug Harry Sokol 01/12/2019 United European Gastroenterology Journal
Sensitive detection of E. coli in artificial seawater by aptamer-coated magnetic beads and direct PCR Jasmina Vidic, Nalini Ramarao, Devon Kavanaugh, ... 01/12/2019 Applied Sciences (Switzerland)
Identification of telomerase RNAs in species of the Yarrowia clade provides insights into the co-evolution of telomerase, telomeric repeats and telomere-binding proteins Cécile Neuvéglise, Hugo Devillers 01/12/2019 Scientific Reports
International consensus conference on stool banking for faecal microbiota transplantation in clinical practice Harry Sokol 01/12/2019 Gut