Laboratoire Physiopathologie et pharmacologie clinique de la douleur

Présentation du laboratoire

Le LPPD s'intéresse aux mécanismes d'hyperalgésie et d'allodynie chez l'homme, c'est-à-dire à des phénomènes neurologiques impliquant une douleur pathologique exacerbée. Ce thème de recherche représente un axe de santé publique majeur concernant jusqu'à 30% de la population totale.
Située sur le site du CHU Ambroise Paré à Boulogne Billancourt, l'unité a une vocation de recherche clinique et travaille en lien étroit avec un nombre important de patients présentant des douleurs pathologiques aiguës ou chroniques. En outre le réseau de cliniciens de l'unité, provenant de différents hôpitaux parisiens, lui offre une véritable richesse d'échantillons et de patients ayant permis de coordonner des essais cliniques majeurs dans le domaine.

Les 20 dernières publications

Titre Auteurs Date de publication Source
Management and intensity of medical end-of-life care in people with colorectal cancer during the year before their death in 2015: A French national observational study Jean Marc Sabate 01/11/2019 Cancer Medicine
Reply to Häuser et al Serge Perrot 01/11/2019 Pain
The opioid epidemic: Helping rheumatologists prevent a crisis Anne Priscille Trouvin, Serge Perrot 01/08/2019 RMD Open
Pain in hypermobile Ehlers-Danlos syndrome: New insights using new criteria Valéria Martinez 01/07/2019 American Journal of Medical Genetics, Part A
Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye) D. Bouhassira 01/07/2019 Pain
Healthcare use by 30,000 patients with irritable bowel syndrome (IBS) in France: A 5-year retrospective and one-year prospective national observational study Jean Marc Sabate 27/06/2019 BMC Gastroenterology
Fibromyalgia: A misconnection in a multiconnected world? Serge Perrot 01/05/2019 European Journal of Pain (United Kingdom)
Translational neuropathic pain research Nadine Attal, D. Bouhassira 01/05/2019 Pain
Burden of drug use for gastrointestinal symptoms and functional gastrointestinal disorders in France: a national study using reimbursement data for 57 million inhabitants Jean Marc Sabate 01/05/2019 Therapeutic Advances in Gastroenterology
The IASP classification of chronic pain for ICD-11: chronic neuropathic pain Serge Perrot 01/01/2019 Pain
The IASP classification of chronic pain for ICD-11: chronic primary pain Serge Perrot 01/01/2019 Pain
The IASP classification of chronic pain for ICD-11: chronic secondary musculoskeletal pain Serge Perrot 01/01/2019 Pain
DOLORisk: Study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved] Nadine Attal, D. Bouhassira 01/01/2019 Wellcome Open Research
Patients’ Global Impression of Change in the management of peripheral neuropathic pain: Clinical relevance and correlations in daily practice Serge Perrot 01/07/2019 European Journal of Pain (United Kingdom)
New concepts of pain Anne Priscille Trouvin, Serge Perrot 01/06/2019 Best Practice and Research: Clinical Rheumatology
Baseline pupil diameter is not a reliable biomarker of subjective sleepiness D. Bouhassira 01/01/2019 Frontiers in Neurology
Drug management of cancer-related peripheral neuropathic pain: A systematic review of the literature Serge Perrot 01/09/2019 Bulletin du Cancer
Low FODMAPs diet, what nutritionist should know about it P. Jouet 01/09/2019 Nutrition Clinique et Metabolisme
Cannabis: A major challenge in pain medicine Anne Priscille Trouvin, Serge Perrot 01/01/2019 Douleur et Analgesie
Fibromyalgia in the workplace: Risk factors for sick leave are related to professional context rather than fibromyalgia characteristics- a French national survey of 955 patients Anne Priscille Trouvin, Serge Perrot 01/01/2019 BMC Rheumatology