Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination |
Lucile Hoch, Celine Bruge, Manon Benabides, Emilie Pellier, Johana Tournois, Gurvan Mahé, Xavier Nissan |
27/04/2022
|
Frontiers in Pharmacology |
Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles |
Cécile Martinat |
01/04/2022
|
Journal of Cachexia, Sarcopenia and Muscle |
Generation of a heterozygous SCN5A knockout human induced pluripotent stem cell line by CRISPR/Cas9 edition |
Lina El Kassar, Karine Giraud-Triboult |
01/04/2022
|
Stem Cell Research |
Clinical Grade Human Pluripotent Stem Cell-Derived Engineered Skin Substitutes Promote Keratinocytes Wound Closure In Vitro |
Raif Eren Ayata, Gilles Lemaitre, Christine Baldeschi |
01/04/2022
|
Cells |
Human-Induced Pluripotent Stem Cell‒Derived Keratinocytes, a Useful Model to Identify and Explore the Pathological Phenotype of Epidermolysis Bullosa Simplex |
Manon Bonnette, Sabrina Martineau, Nathalie Holic, Gilles Lemaitre, Cécile Martinat, Christine Baldeschi |
01/01/2022
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Journal of Investigative Dermatology |
AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A |
Patrick Aubourg |
01/12/2021
|
Nature Communications |
Optogenetically controlled human functional motor endplate for testing botulinum neurotoxins |
Juliette Duchesne de Lamotte, Jérôme Polentes, Florine Roussange, Léa Lesueur, Pauline Feurgard, Anselme L. Perrier, Cécile Martinat |
01/12/2021
|
Stem Cell Research and Therapy |
Contribution of human pluripotent stem cell-based models to drug discovery for neurological disorders |
Alexandra Benchoua, Marie Lasbareilles, Johana Tournois |
01/12/2021
|
Cells |
Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome |
Sandra Pourtoy-Brasselet, Axel Sciauvaud, Maria Gabriela Boza-Moran, Michel Cailleret, Margot Jarrige, Hélène Polvèche, Jérôme Polentes, Cécile Martinat, Marc Peschanski, Laetitia Aubry |
04/11/2021
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American Journal of Human Genetics |
Dual imaging of dendritic spines and mitochondria in vivo reveals hotspots of plasticity and metabolic adaptation to stress |
Nicolas Tricaud |
01/11/2021
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Neurobiology of Stress |
Exosomes: Multi-faceted natural intercellular messengers as new candidates for the treatment of myopathies? |
Judith Lorant |
01/11/2021
|
Medecine/sciences |
Modulation of alternative splicing during early infection of human primary B lymphocytes with Epstein-Barr virus (EBV): a novel function for the viral EBNA-LP protein |
Hélène Polvèche |
11/10/2021
|
Nucleic Acids Research |
Chimeric embryos and pseudo-embryos: An alternative to human embryos for research |
Cécile Martinat |
01/08/2021
|
Medecine/sciences |
Emerging opportunities in human pluripotent stem-cells based assays to explore the diversity of botulinum neurotoxins as future therapeutics |
Juliette Duchesne de Lamotte, Anselme L. Perrier, Cécile Martinat |
02/07/2021
|
International Journal of Molecular Sciences |
Hutchinson-Gilford progeria syndrome: Rejuvenating old drugs to fight accelerated ageing |
Solenn M. Guilbert, Xavier Nissan |
01/06/2021
|
Methods |
Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1 |
Hélène Polvèche |
05/05/2021
|
Frontiers in Cellular Neuroscience |
Human cytomegalovirus infection is associated with increased expression of the lissencephaly gene PAFAH1B1 encoding LIS1 in neural stem cells and congenitally infected brains |
Alexandra Benchoua |
01/05/2021
|
Journal of Pathology |
Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice |
Morgane Louessard, Patricia Lino, Anselme L. Perrier |
01/03/2021
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Science advances |
Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification |
Hynek Wichterle |
01/03/2021
|
Development (Cambridge) |
Myogenesis modelled by human pluripotent stem cells: a multi-omic study of Duchenne myopathy early onset |
Virginie Mournetas, Emmanuelle Massouridès, Jean Baptiste Dupont, Hélène Polvèche, Margot Jarrige, Alan R.L. Dorval, Christian Pinset |
01/02/2021
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Journal of Cachexia, Sarcopenia and Muscle |