Biomarqueurs en cancérologie et onco-hématologie

Présentation du laboratoire

Les activités de recherche du laboratoire BECCOH portent sur les essais cliniques et le développement de biomarqueurs, pour les patients atteints de cancers cutanés, digestifs ou pulmonaires, ou d'histocytoses. Les équipes du laboratoire visent des transversalités fortes en particulier autour du développement et de la validation de biomarqueurs prédictifs et pronostiques permettant une spécification toujours plus poussée de la prise en charge thérapeutique des patients.Le laboratoire BECCOH dispose d'une plateforme de pathologie histologique et moléculaire pour l'étude des néoplasies, et est adossé à un centre de ressources biologiques (CRB) certifié par AFNOR à la norme NF96-900.

Les 20 dernières publications

Titre Auteurs Date de publication Source
Rational testing for gene fusion in colorectal cancer: MSI and RAS-BRAF wild-type metastatic colorectal cancer as target population for systematic screening Catherine Julié, Cristi Marin, Jean François Emile 01/07/2022 European Journal of Cancer
Investigation of the RB1-SOX2 axis constitutes a tool for viral status determination and diagnosis in Merkel cell carcinoma Astrid Blom, P. Saiag 01/06/2022 Virchows Archiv
Tumor budding is an independent prognostic factor in stage III colon cancer patients: a post-hoc analysis of the IDEA-France phase III trial (PRODIGE-GERCOR) Jean François Emile 01/06/2022 Annals of Oncology
Consensus statement by the French Society of Endocrinology (SFE) and French Society of Pediatric Endocrinology & Diabetology (SFEDP) on diagnosis of Cushing's syndrome Marie Laure Raffin-Samson 01/04/2022 Annales d'Endocrinologie
MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis Jean François Emile, Omar Abdel-Wahab 01/04/2022 Leukemia
Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma P. Saiag 01/04/2022 Clinical Cancer Research
Monitoring of plasma concentrations of dabrafenib and trametinib in advanced BRAFV600<sup>mut</sup> melanoma patients M. Raynal, P. Saiag, E. Funck-Brentano 01/03/2022 Annales de Dermatologie et de Venereologie
Impact of the French COVID-19 pandemic lockdown on newly diagnosed melanoma delay and severity A. Roger, Astrid Blom, Christine Longvert, P. Saiag, E. Funck-Brentano 01/03/2022 Journal of the European Academy of Dermatology and Venereology
<sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography imaging for the diagnosis of immune checkpoint inhibitor-associated myocarditis E. Funck-Brentano 01/02/2022 Archives of Cardiovascular Diseases
A comprehensive overview of tumour deposits in colorectal cancer: Towards a next TNM classification Jean François Emile 01/02/2022 Cancer Treatment Reviews
ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition Zofia Hélias-Rodzewicz, Jean Donadieu, Jean François Emile 13/01/2022 Blood
Gene expression profile of high PD-L1 non-small cell lung cancers refractory to pembrolizumab Paul Takam Kamga, Marie Mayenga, Adrien Costantini, Catherine Julié, Jean François Emile, Etienne Giroux Leprieur 01/01/2022 Cancer Immunology, Immunotherapy
Acute generalized exanthematous pustulosis caused by gemcitabine after nivolumab in metastatic lung adenocarcinoma followed by a dramatic tumor response: A case report Adrien Costantini, Etienne Giroux Leprieur 01/01/2022 Thoracic Cancer
Cutaneous histiocytoses in children Jean François Emile 01/01/2022 Histopathology
High Circulating Sonic Hedgehog Protein Is Associated With Poor Outcome in EGFR-Mutated Advanced NSCLC Treated With Tyrosine Kinase Inhibitors Paul Takam Kamga, Adrien Costantini, Catherine Julié, Jean François Emile, Etienne Giroux Leprieur 14/12/2021 Frontiers in Oncology
Maintenance of a Gastric Pacemaker in the Excluded Stomach During a Roux-en-Y Gastric Bypass Procedure in a Patient with Obesity, Type 1 Diabetes and Refractory Gastroparesis Marie Laure Raffin-Sanson 01/12/2021 Obesity Surgery
Malignant histiocytosis with a Langerhans cell subtype: A report on the diagnostic and therapeutic challenge Jean François Emile 01/12/2021 Blood Cells, Molecules, and Diseases
Cutaneous toxicities from targeted therapies used in oncology: Literature review of clinical presentation and management Solène Huynh Dagher, Astrid Blom, E. Funck-Brentano 01/12/2021 International Journal of Women's Dermatology
Plasma biomarkers screening by multiplex ELISA assay in patients with advanced non-small cell lung cancer treated with immune checkpoint inhibitors Adrien Costantini, Paul Takam Kamga, Catherine Julié, Thierry Chinet, Jean François Emile, Etienne Giroux Leprieur 01/12/2021 Cancers
CARMN-NOTCH2 fusion transcript drives high NOTCH2 expression in glomus tumors of the upper digestive tract Nicolas Girard, Cristi Marin, Zofia Hélias-Rodzewicz, Catherine Julié, Jean François Emile 01/11/2021 Genes Chromosomes and Cancer

Nombre de publications du laboratoire par domaine scientifique (2016-2021)

Chaque publication du laboratoire peut être rangée dans une ou plusieurs disciplines scientifiques : la figure ci-dessus présente le nombre de publications du laboratoire pour chaque discipline de la classification ASJC (Elsevier)