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Biomarqueurs en cancérologie et onco-hématologie

Présentation du laboratoire

Les activités de recherche du laboratoire BECCOH portent sur les essais cliniques et le développement de biomarqueurs, pour les patients atteints de cancers cutanés, digestifs ou pulmonaires, ou d'histocytoses. Les équipes du laboratoire visent des transversalités fortes en particulier autour du développement et de la validation de biomarqueurs prédictifs et pronostiques permettant une spécification toujours plus poussée de la prise en charge thérapeutique des patients.Le laboratoire BECCOH dispose d'une plateforme de pathologie histologique et moléculaire pour l'étude des néoplasies, et est adossé à un centre de ressources biologiques (CRB) certifié par AFNOR à la norme NF96-900.

Les 20 dernières publications

Titre Auteurs Date de publication Source
Impact of socioeconomic status in patients hospitalised for COVID-19 in the Greater Paris area Etienne Giroux Leprieur, Sébastien Beaune, Marion Pépin, ... 01/12/2020 European Respiratory Journal
Central nervous system involvement in Erdheim-Chester disease: An observational cohort study J. Donadieu, Fleur Cohen-Aubart, Jean François Emile, ... 17/11/2020 Neurology
Extracellular Vesicle-Dependent Communication Between Mesenchymal Stromal Cells and Immune Effector Cells Paul Takam Kamga 06/11/2020 Frontiers in Cell and Developmental Biology
HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development Paul Takam Kamga 05/11/2020 Frontiers in Cell and Developmental Biology
The contribution of micrornas to the inflammatory and neoplastic characteristics of erdheim–chester disease Jean François Emile 01/11/2020 Cancers
The TNM classification in practice Etienne Giroux Leprieur 01/10/2020 Revue des Maladies Respiratoires Actualites
Efficacy of late concurrent hypofractionated radiotherapy in advanced melanoma patients failing anti-PD-1 monotherapy P. Saiag, Elisa Funck-Brentano, Christine Longvert, ... 15/09/2020 International Journal of Cancer
Childhood Langerhans cell histiocytosis with severe lung involvement: A nationwide cohort study Jean François Emile, S. Heritier 09/09/2020 Orphanet Journal of Rare Diseases
Small molecule inhibitors of microenvironmental wnt/β-catenin signaling enhance the chemosensitivity of acute myeloid leukemia Paul Takam Kamga 01/09/2020 Cancers
Prognostic Value of Tumor Deposits for Disease-Free Survival in Patients With Stage III Colon Cancer: A Post Hoc Analysis of the IDEA France Phase III Trial (PRODIGE-GERCOR) Jean François Emile 01/01/2020 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
BRAF-mutated histiocytosis of the skull lacking the expression of Langerhans cell markers Jean François Emile 01/04/2020 Clinical Neuropathology
European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 1. epidemiology, diagnostics and prevention P. Saiag 01/03/2020 European Journal of Cancer
European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment P. Saiag 01/03/2020 European Journal of Cancer
Lung Involvement in Destombes-Rosai-Dorfman Disease: Clinical and Radiological Features and Response to the MEK Inhibitor Cobimetinib Jean François Emile 01/02/2020 Chest
Predictive value of soluble PD-1, PD-L1, VEGFA, CD40 ligand and CD44 for nivolumab therapy in advanced non-small cell lung cancer: A case-control study Etienne Giroux Leprieur 01/02/2020 Cancers
Erdheim-chester disease with concomitant rosai-dorfman like lesions: A distinct entity mainly driven by MAP2K1 Jean François Emile, Zofia Hélias-Rodzewicz 01/01/2020 Haematologica
Functional dosing of mesenchymal stromal cell-derived extracellular vesicles for the prevention of acute graft-versus-host-disease Paul Takam Kamga 01/05/2020 Stem Cells
Use of targeting therapy in Erdheim-Chester disease: A case report with neurologic involvement Jean François Emile 01/06/2020 Revue de Medecine Interne
Loss of SMARCB1 expression in colon carcinoma Jean François Emile 01/01/2020 Cancer Biomarkers
Coexistence of Autoimmune Hyper- And Hypothyroidism in a Kindred with Reduced Sensitivity to Thyroid Hormone Marie Laure Raffin-Sanson, Laure Cazabat 01/09/2020 European Thyroid Journal