Laboratoire de Chimie Physique, Université Paris Sud
The Pasarow Mass Spectrometry Laboratory
The Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, UCLA, USA
Vendredi 9 novembre à 14h (salle Magat) :
“Integral Membrane Proteins : top-down mass spectrometry meets structural proteomics”
Membrane proteins constitute a critical segment of the proteome but their physical properties challenge many analytical technologies. For twenty years liquid chromatography coupled with electrospray ionization mass spectrometry has yielded fundamental information for structural biologists studying the structure and function of membrane proteins. Recent developments in native mass spectrometry and ion mobility raise the exciting potential that mass spectrometry will take on a driving role in structural biology in future.