Cancer treatment : innovative therapeutic strategies based on the use of the tumor targeted radiation modalities and nanoagents
The improvement and personalization of treatments to increase cure rates and reduce side effects of cancer treatments and to reduce the costs of these treatments is a major societal issue.
In answer to these major medical, cognitive and societal challenges, we propose an ambitious project concerning the research and development of innovative protocols in radiotherapy based on the concomitant use of new sources of irradiation and nanoagents or radio-sensitizing molecules.
New strategies, original tools and products as well as the understanding of their properties and mode of actions will emanate from this project.
Nano-objects and ultra-high dose rate sources exploitation is a niche of research that is growing in Europe and in the World to improve cancer treatments by radiotherapy.
Project financing for the phase 2 (June 2018 to June 2020)
First annual meeting of NanoTheRad project
The first annual meeting of NanoTheRad project will take place at Saint-Aubin, on January 11th, 2018 at the Synchrotron Soleil amphitheater. The partners will discuss and assess the project tasks’ progresses initiated in the beginning of the project, bring forward the tools and expertise that everyone can share within the consortium and will facilitate the interactions to generate new collaborations.
Sponsoring of the International conference : Advanced Radiotherapy, Generated by Exploiting Nanoprocesses and Technologies
Chair: Prof. Sandrine Lacombe - U.Paris-Sud, U.Paris-Saclay
22-24 Jan 2018, CNRS, Univ. Paris-Saclay, Gif-sur-Yvette (Paris region), France
Cancer remains a major European health concern. More than 50% of patients receive radiotherapy as part of their cancer treatment. The main limitations of this treatment are the lack of tumour selectivity, which causes severe side effects, and the radioresistance of tumours. Highly promising approaches to improve the performances of radiation-based therapies include advanced radiation protocols (such as fast ion beam radiation or ultra-high-dose rate radiation) and nanoparticles-enhanced therapies.
This international conference brings together World leading researchers of different disciplines: physicists and medical physicists, chemists, biologists, medical doctors and SMEs with the aim of presenting their results of exploiting and understanding the nanoscale processes, towards the development and optimization of new nanodrugs together with novel radiation protocols – a high-excellence effort that should lead to a new era for radiotherapy with subsequent economic and quality of life benefits for the population.
Steering Committe members:
|Gérard Baldacchino - LIDYL CEA (co-coordinator)||Charles Fouillade - UMR3347/U1021 - Institut Curie|
|Marie Dutreix - UMR3347/U1021 - Institut Curie (co-coordinator)||Pierre-Marie Girard - UMR3347/U1021 - Institut Curie|
|Sandrine Lacombe - ISMO UPSud (co-coordinator)||Ruxandra Gref - ISMO UPSud|
|Fabrice Confalonieri - I2BC UPSud||Erika Porcel - ISMO UPSud|
|Jozo Delic - IRCM CEA||Célio Pouponnot - UMR3347/U1021 - Institut Curie|
|Sandrine Dobosz - LIDYL CEA||Patricia Noguiez-Hellin - Institut Curie (project manager)|
Permanent invited member:
Alessandro Flacco - LOA ENSTA