[{"command":"insert","method":null,"selector":".course-modal-ajax-placeholder-963955","data":"\u003Cdiv class=\u0022container content-rte\u0022\u003E\n  \u003Cdiv class=\u0022row\u0022\u003E\n    \u003Cdiv class=\u0022box col-md-6 bg-primary text-white\u0022\u003E\n      \u003Ch2 class=\u0022h1 text-left\u0022\u003E  Advanced Functional Genomics\n\u003C\/h2\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EECTS :\n          3\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ESemester:\n          Semestre 1\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ED\u00e9tail du volume horaire\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ELecture:\u003C\/span\u003E\n                                      \u003Cspan\u003E15\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                              \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003EDirected study:\u003C\/span\u003E\n                                      \u003Cspan\u003E7.5\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                                            \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ELangue d\u0026#039;enseignement\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EAnglais\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EEnseignement \u00e0 distance\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003Enon\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n    \u003Cdiv class=\u0022box col-md-6\u0022\u003E\n                    \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EProgramme \/ plan \/ contenus\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EAt the end of this course, the students cill be able to\u003C\/p\u003E\n\u003Cp\u003E-Enumerate and differentiate large-scale sequencing technology driven-approaches, i.e. RNA-seq, ChIP-seq, Methyl-seq, WGBS, ATAC-seq, Hi-C\u003C\/p\u003E\n\u003Cp\u003E-Specify the distinct steps of the analysis workflows from raw data to pathway analysis (read mapping strategies, transcript assembly, data normalization, isoform-specific or differential gene expression analysis) for both quantitative and qualitative analysis of transcriptomic data\u003C\/p\u003E\n\u003Cp\u003E-Understand the limits of bulk RNAseq in regard to Single-cell approach\u003C\/p\u003E\n\u003Cp\u003E-Describe the principle of data production and analysis of ChIP-seq from peak calling to data visualization\u003C\/p\u003E\n\u003Cp\u003E-Explain the methods of data exploration: common tools of genes \u0026amp;\/or samples classification and functional annotation\u003C\/p\u003E\n\u003Cp\u003E-Determine which technology to use among a broad spectrum of functional genomics methods to address specific biological questions\u003C\/p\u003E\n\u003Cp\u003E-Interpret results of the high-throughput data in a scientifically stringent manner\u003C\/p\u003E\n\u003Cp\u003E-Enumerate applications of these sequencing data in health and precision medicine\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EObjectifs d\u0026#039;apprentissage\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EThis course provides a thorough knowledge of functional genomic technologies to study distinct levels of gene regulation: transcriptomic, epigenomic \u0026amp; dynamic of chromatin structure.\u003C\/p\u003E\n\u003Cp\u003EIt will train student to extract pertinent data from scientific articles, identify their limits and synthetize them in a \u0022journal club format.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EOrganisation g\u00e9n\u00e9rale et modalit\u00e9s p\u00e9dagogiques\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EThe course consists in lectures, analysis of genomic studies based on several publications during tutorials and oral presentations of research work will be performed as seminars by the students.\u003C\/p\u003E\n\u003Cp\u003EA particular focus on the use of these tools in the context of disease study and precision medicine (sample classification, diagnostic, prognostic tools and pathways analysis for target identification).\u003C\/p\u003E\n\u003Cp\u003EThe students will be evaluated through oral presentation based on scientific publications and continuous assessment during the course.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EComp\u00e9tences\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EC2.1 : Actualiser ses connaissances th\u00e9oriques et technologiques par une veille dans son domaine en relation avec l\u2019\u00e9tat de la recherche.\u003C\/p\u003E\n\u003Cp\u003EC3.2 : Structurer et pr\u00e9senter des donn\u00e9es et concepts scientifiques \u00e0 des sp\u00e9cialistes ou \u00e0 des n\u00e9ophytes.\u003C\/p\u003E\n\u003Cp\u003EC3.3 : Argumenter les choix m\u00e9thodologiques et les interpr\u00e9tations d\u2019une \u00e9tude.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ENature de l\u0026#039;\u00e9valuation\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EEvaluation Continue non Int\u00e9grale\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n","settings":null}]