[{"command":"insert","method":null,"selector":".course-modal-ajax-placeholder-958546","data":"\u003Cdiv class=\u0022container content-rte\u0022\u003E\n  \u003Cdiv class=\u0022row\u0022\u003E\n    \u003Cdiv class=\u0022box col-md-6 bg-primary text-white\u0022\u003E\n      \u003Ch2 class=\u0022h1 text-left\u0022\u003E  Genetics of complex pathologies\n\u003C\/h2\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EECTS :\n          3\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ESemester:\n          Semestre 1\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ED\u00e9tail du volume horaire\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ELecture:\u003C\/span\u003E\n                                      \u003Cspan\u003E9\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                              \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003EDirected study:\u003C\/span\u003E\n                                      \u003Cspan\u003E13.5\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                                            \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ELangue d\u0026#039;enseignement\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EAnglais\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EEnseignement \u00e0 distance\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003Enon\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n    \u003Cdiv class=\u0022box col-md-6\u0022\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EPr\u00e9requis\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EFundamentals of formal genetics.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EProgramme \/ plan \/ contenus\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003E1. Introduction\u003Cbr\u003E\na. Types of human diseases and factors involved\u003Cbr\u003E\nb. Issues raised by multifactorial diseases\u003Cbr\u003E\n2. \u0026nbsp; \u0026nbsp;Data production methods\u003Cbr\u003E\n3. \u0026nbsp; \u0026nbsp;Data quality control\u003Cbr\u003E\na. \u0026nbsp; \u0026nbsp;Missing data\u003Cbr\u003E\nb. \u0026nbsp; \u0026nbsp;Hardy-Weinberg model\u003Cbr\u003E\nc. \u0026nbsp; \u0026nbsp;Principal component analysis\u003Cbr\u003E\nd. \u0026nbsp; \u0026nbsp;Other\u003Cbr\u003E\n4. \u0026nbsp; \u0026nbsp;Search for causal genetic variants\u003Cbr\u003E\na. \u0026nbsp; \u0026nbsp;Association analyses on family data (Transmission Disequilibrium Test)\u003Cbr\u003E\nb. Association analyses on population data (case-control studies)\u003Cbr\u003E\nc. \u0026nbsp; \u0026nbsp;Pan-genomic association studies\u003Cbr\u003E\n5. \u0026nbsp; \u0026nbsp;Generalizations\u003Cbr\u003E\na. \u0026nbsp; \u0026nbsp;Association analysis for rare variants\u003Cbr\u003E\nb. \u0026nbsp; \u0026nbsp;Search for interactions\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EObjectifs d\u0026#039;apprentissage\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003E- Identify the genetic analysis methods to be used for a given problem\u003Cbr\u003E\n- Describe methods for producing genetic data on a large scale\u003Cbr\u003E\n- Be familiar with various examples of complex pathologies\u003Cbr\u003E\n- Select the appropriate statistical tools\u003Cbr\u003E\n- Perform adequate data quality checks\u003Cbr\u003E\n- Conduct a genetic association study\u003Cbr\u003E\n- Know how to interpret the results of a genetic association study\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EOrganisation g\u00e9n\u00e9rale et modalit\u00e9s p\u00e9dagogiques\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EThe course consists of lectures to learn the theoretical basics. Tutorials will allow to students to put theoretical concepts into practice.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EComp\u00e9tences\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EC1.1. Formuler des probl\u00e9matiques et des hypoth\u00e8ses de travail permettant la conception et la r\u00e9alisation d\u2019un projet dans son domaine d\u2019expertise et \/ou \u00e0 l\u2019interface de plusieurs domaines en biologie.\u003C\/p\u003E\n\u003Cp\u003EC2.3. Se former \u00e0 de nouveaux outils technologiques.\u003C\/p\u003E\n\u003Cp\u003EC3.1. Structurer et pr\u00e9senter des donn\u00e9es et concepts scientifiques \u00e0 des sp\u00e9cialistes ou \u00e0 des n\u00e9ophytes.\u003C\/p\u003E\n\u003Cp\u003EC3.2. Argumenter les choix m\u00e9thodologiques et les interpr\u00e9tations d\u2019une \u00e9tude.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EBibliographie\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003ELaird N. M., Lange C. The Fundamentals of Modern Statistical Genetics. Springer. Hardcover, 2011, 226 p. ISBN 978-1-4419-7338-2\u003C\/p\u003E\n\u003Cp\u003EGibson G, Muse S.V. Pr\u00e9cis de G\u00e9nomique. De Boek. 2004, 347p. ISBN 9782804143343\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ENature de l\u0026#039;\u00e9valuation\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EEvaluation Continue non Int\u00e9grale\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n","settings":null}]