[{"command":"insert","method":null,"selector":".course-modal-ajax-placeholder-955500","data":"\u003Cdiv class=\u0022container content-rte\u0022\u003E\n  \u003Cdiv class=\u0022row\u0022\u003E\n    \u003Cdiv class=\u0022box col-md-6 bg-primary text-white\u0022\u003E\n      \u003Ch2 class=\u0022h1 text-left\u0022\u003E  Prot\u00e9omique\n\u003C\/h2\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EECTS :\n          6\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n                  \u003Cdiv class=\u0022field-spacing\u0022\u003E\n        \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ESemester:\n          Semestre 1\n        \u003C\/div\u003E\n      \u003C\/div\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ED\u00e9tail du volume horaire\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003ELecture:\u003C\/span\u003E\n                                      \u003Cspan\u003E35\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003EPractical study :\u003C\/span\u003E\n                                      \u003Cspan\u003E3\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                          \u003Cspan class=\u0022field__label h4 mt-5 \u0022\u003EDirected study:\u003C\/span\u003E\n                                      \u003Cspan\u003E12\u003C\/span\u003E\n                      \u003C\/div\u003E\n                                                            \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ELangue d\u0026#039;enseignement\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EFran\u00e7ais\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EEnseignement \u00e0 distance\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003Enon\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n    \u003Cdiv class=\u0022box col-md-6\u0022\u003E\n            \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EPr\u00e9requis\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003EPr\u00e9-requis recommand\u00e9s : biochimie des prot\u00e9ines et\/ou chimie analytique et\/ou spectrom\u00e9trie de masse.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EProgramme \/ plan \/ contenus\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003E1- Etat des lieux des analyses prot\u00e9omiques.\u003Cbr\u003E\n2- M\u00e9thodes de spectrom\u00e9trie de masse adapt\u00e9es \u00e0 l\u2019analyse des peptides et prot\u00e9ines\u003Cbr\u003E\n-Principe des modes d\u2019ionisation (MALDI, ESI)\u003Cbr\u003E\n-Principe des analyseurs de masse simples et hybrides (TOF-TOF, Q-TOF, Trappe, Orbitrap, FTICR...) \u0026nbsp;\u0026nbsp;\u003Cbr\u003E\n-Principe de la fragmentation\u003Cbr\u003E\n-Comparaison des sp\u00e9cificit\u00e9s et utilit\u00e9s des diff\u00e9rentes techniques.\u003Cbr\u003E\n3- Strat\u00e9gies prot\u00e9omiques\u003Cbr\u003E\n-Identifications des prot\u00e9ines (strat\u00e9gies classiques et hauts d\u00e9bits d\u00e9di\u00e9es \u00e0 l\u0027analyse de m\u00e9langes tr\u00e8s complexes)\u003Cbr\u003E\n-Quantification des prot\u00e9ines (m\u00e9thodes globales ou cibl\u00e9es).\u003Cbr\u003E\n-Caract\u00e9risations des modifications post-traductionnelles connues ou inconnues\u003Cbr\u003E\n-Interactions prot\u00e9ine-prot\u00e9ine\u003Cbr\u003E\n-Informations structurales: interactions non covalentes et caract\u00e9risation de d\u00e9terminants structuraux\u003Cbr\u003E\n4- M\u00e9thodes de pr\u00e9paration, s\u00e9paration et enrichissement des prot\u00e9ines et peptides\u003Cbr\u003E\n-Pr\u00e9parations classiques des \u00e9chantillons, \u00e9lectrophor\u00e8se, chromatographie.\u003Cbr\u003E\n-Cas des modifications post-traductionnelles (modifications classiques, glycosylations, phosphorylations, nouvelles modifications, \u2026)\u003Cbr\u003E\n-Cas des prot\u00e9ines membranaires.\u003Cbr\u003E\n-M\u00e9thodes d\u2019enrichissement.\u003Cbr\u003E\n5- Analyses de donn\u00e9es (cours et TD)\u003Cbr\u003E\n-Mesures de masse d\u0027une prot\u00e9ine, d\u0027un m\u00e9lange de peptides\u003Cbr\u003E\n-Fragmentation de peptides et prot\u00e9ines : principe et analyse de spectres de fragmentation\u003Cbr\u003E\n- Cas pratiques\u0026nbsp;\u003Cbr\u003E\n- Analyses des donn\u00e9es haut d\u00e9bit (utilisation d\u0027outils IA)\u003Cbr\u003E\n- Analyses statistiques\u003Cbr\u003E\n6-Atelier TP sur une plateforme de prot\u00e9omique: mesures de masse et d\u2019identification de prot\u00e9ines.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EOrganisation g\u00e9n\u00e9rale et modalit\u00e9s p\u00e9dagogiques\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003ECette unit\u00e9 d\u0027enseignement du M2 Ing\u00e9nierie et Chimie des Biomol\u00e9cules est organis\u00e9e sous forme de cours hebdomadaire, entre septembre et d\u00e9cembre.\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003EModalit\u00e9s p\u00e9dagogiques particuli\u00e8res\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003E\u003Cp\u003ELieux d\u0027enseignement : I2BC, campus CNRS Gif-sur-Yvette\u003C\/p\u003E\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n                        \u003Cdiv class=\u0022field-spacing\u0022\u003E\n      \u003Cdiv class=\u0022field__label h3 dash\u0022\u003ENature de l\u0026#039;\u00e9valuation\u003C\/div\u003E\n                        \u003Cdiv class=\u0022mt-5 text-justify\u0022\u003E\n                                      \u003Cspan\u003EEvaluation Continue non Int\u00e9grale\u003C\/span\u003E\n                      \u003C\/div\u003E\n                  \u003C\/div\u003E\n      \u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n","settings":null}]