Published on 14 November 2018

GO Paris-Saclay and Evry Paris-Saclay, two teams of students from Université Paris-Saclay, each won a gold medal at the International Genetically Engineered Machine competition (iGEM 2018) held in Boston in late October. The Evry Paris-Saclay team was also nominated in the "Best New Composite Part" category for BBa_K2675042, a cassette of expression and secretion of hexapeptide SAIRGA in E. coli.

The Evry Paris-Saclay team, composed of students from Université Paris-Saclay (14 students from Université d’Evry, 1 student from Université Paris-Sud) and one student from Université Paris 1 Panthéon-Sorbonne, has developed a synthetic biology project. Entitled "PepTalk: Repurposing Bacteriophage Peptide Signals For Expanded Bacterial Communication Vocabulary," it provides the foundations for the development of an orthogonal intercellular communication system in E. coli (see project at

The project was developed with the financial support of several partners including Université d’Evry, Genopole and Université Paris-Saclay & Investissements d'Avenir through the supervision of iSSB laboratories within UMR 8030 Génomique Métabolique (CEA-CNRS-UEVE, Evry), Micalis (INRA-APT, Jouy-en-Josas) and through access to the Genopole abSYNTH synthetic biology platform.

The Paris-Saclay GO team, composed of students from Université Paris-Saclay (Université Paris-Sud, AgroParisTech and ENSTA), has developed a synthetic biology project entitled "MethotrExit: The HeteroGenious Cleaning Factory." The project is based on the development of strains capable of effectively degrading a hospital wastewater pollutant (methotrexate) and on the design of a synthetic expression system to generate a division of labor in populations of bacteria (see project at

This project was developed thanks to financial support from several partners, including I2BC (UMR 9198), Université Paris-Saclay & Investissements d'Avenir and Université Paris-Sud (including the project FSDIE, Magister degree in Biology and Second year of master's in fundamental microbiology in the Biology-Health curriculum) and through the supervision of the I2BC laboratories (UMR 9198).