Published on 1 March 2019
Research

On the margins of Sidaction 2019, an annual event to raise funds towards research on AIDS, the Laboratory of Pharmacology and Applied Biology (LBPA - CNRS, ENS Paris-Saclay), is organizing the 3rd edition of the "Research at the Service of Prevention" day. It will take place on March 28, and is organised in partnership with the École Normale Supérieure Paris-Saclay and the support of Université Paris-Saclay.

This day of meetings and discussion around the theme of HIV / AIDS will be led by experts recognized in their field to take stock of research currently conducted on HIV, whether basic, clinical, social or preventive research.

For this 3rd edition, Dr. Françoise BARRE-SINOUSSI, Nobel Prize for Medicine 2008, and co-discoverer of the AIDS virus and President of the association Sidaction, will speak on the theme: "HIV / AIDS - the challenges of the 21st century"

To educate is to protect !

In 2017, HIV represented 1 infection every 17 seconds, or 5,000 new infections per day. Around the world, nearly 37 million people are living with HIV, 59% of whom are on antiretroviral treatment, 18 million people have been newly infected and 1 in 4 HIV-positive are unaware that they have the virus. In France, there were 6,000 new infections of which 14% were among 25 year-olds and less and 22% were among 50 year-olds +.

AIDS is perceived today as a "chronic pathology". It has gone from the status of "threat" to "acceptable risk". This results in the decline of preventive behavior, which has increased the difficulty to control the epidemic. Today, prevention remains the most effective way to fight this pandemic.

The event is free and open to all upon registration. It is an opportunity to meet the players involved in the fight against AIDS and to discover their work, as well as raise funds for the benefit of the Sidaction association.

Join us on Thursday, March 28, 2019

at the École Normale Supérieure Paris-Saclay (in Cachan) to find out more!

HIV research at LBPA

Researchers commit themselves every day in the fight against AIDS to understand the way the virus works, find treatments, vaccines, effective means of prevention... This is the case of the LBPA.

Indeed, since 1987, the "retrovirus theme" is omnipresent in the laboratory, initially introduced by its Director, Professor Claude PAOLETTI to study three essential steps in the retroviral cycle: penetration, reverse transcription and integration. It was more focused on the study of integrase in the 90s under the direction of Professor Christian AUCLAIR. Then the laboratory specialized in the pharmacological study of anti-integrase compounds including the development of in vitro integration tests with the arrival of Dr. Jean-François MOUSCADET.

Today, research on HIV-1 continues with, among others, Dr. Olivier DELELIS, Research Director at the CNRS, and Dr. Clémence RICHETTA, Associate Professor at ENS Paris-Saclay who are working on resistance to anti-integrase; Dr. Philippe FOSSE and Olivier MAUFFRET, Research Directors at the CNRS who are studying the nucleo-capsid protein of HIV-1 (NCp7).

 

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