Published on 21 May 2019
Martine Caroff, Prix européen de la femme innovatrice 2019, image extraite de la video réalisée par EU Science & Innovation

Martine Caroff has just received the EU Prize for Women Innovators 2019 for her company LPSBioScience at the VivaTech conference in Paris, on May 18, 2019.

The European Union wants to encourage women scientists and innovators to overcome the gender inequality that exists at the entrepreneurial level. Martine Caroff—who has followed her entire scientific curriculum on the University of Paris-Saclay campus —founded in 2011 a first innovative biotech, LPS-BioSciences (, specialized in endotoxins, molecules of the bacterial membrane, used as antigens or vaccine adjuvants.

This innovative company located in Essonne, on the University of Paris-Saclay campus, supports manufacturers in developing new vaccines and addressing regulatory issues related to endotoxins. The objective of LPS-BioSciences is to produce these molecules on a large scale for the needs of the pharmaceutical industry and to become a key player in vaccines.

The company was created based on a university patent, of which it is the author, and describes an innovative method for producing molecules useful for antibacterial control. The scientist, who has been already distinguished by numerous prizes, including the Innovation Prize of the Université Paris-Sud and the Conseil Général de l'Essonne in 2006, has achieved a major breakthrough in the CNRS and Université Paris-Sud biochemistry research group that she leads.

Martine Caroff was one of the three winners of the EU Prize for Women Innovators after founding a second biotechnological company, HEPHAISTOS-Pharma.

“In 2018, we created HEPHAISTOS-Pharma (, a biotech that uses the immuno-stimulating power of these molecules in the fight against cancer,” said Caroff. She has decided to invest all of the prize money into this new company because like Europe, Université Paris-Saclay or the Essonne Chamber of Commerce, she believes in her innovations. These new treatments will allow immunotherapies to become more effective and cure more patients.

Biography : 

Martine Caroff, Founder and Scientific Director of LPS-BIOSCIENCES and HEPHAISTOSPharma. Martine Caroff holds two doctorates, including a PhD in Science from the University of Paris-Sud in 1982. After a post-doctoral fellowship at the NRC in Canada, she became an international endotoxin specialist and for the past 25 years has led a research team at the CNRS at the University of Paris- Sud. Inventor of three patents, she has been awarded several innovation prizes and for the creation of the company LPSBIOSCIENCES in 2011, in the field of vaccines and diagnostics, then HEPHAISTOS- Pharma in 2018 in the field of immunotherapy against cancer. She is the author of 111 international publications, 3 patents and book chapters on bacterial endotoxins. She regularly gives courses on business creation to encourage the younger generations of female researchers to innovate and become entrepreneurs.