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Institut Galien Paris-Saclay

Laboratory presentation

The Institut Galien Paris Sud (IGPS) is a major international player in nanomedicine research. His goal is to develop nanotechnologies to deliver drugs to target cell populations and modulate their effects or for in vitro diagnostics and in vivo. The unit enjoys excellent international visibility thanks to its numerous publications and communications. His innovative work on nanomedicine attracts many collaborations, as evidenced by registered patents and industrial contracts. It is divided into three main poles (Physical Chemistry, Galenic Pharmaceuticals, Analytics) around which 7 teams with complementary skills are concentrated. It is a member of LabEx Lermit and NanoSaclay as well as the Paris-Sud Institute of Therapeutic Innovation (IPSIT). The IGPS has numerous scientific facilities grouped into common services for some throughout the site, which are available to everyone. They allow an optimal collaboration between the different teams of the unit and also attract external teams.

The 20 latest publications

Title Authors Publication date Source
Novel liposome-like assemblies composed of phospholipid-porphyrin conjugates with photothermal and photodynamic activities against bacterial biofilms Rayene Benmahmoudi, Christophe Regeard 07/25/22 International Journal of Pharmaceutics
Formation and stabilization of multiple w/o/w emulsions encapsulating catechin, by mechanical and microfluidic methods using a single pH-sensitive copolymer: Effect of copolymer/drug interaction Noémi Bodin-Thomazo, Florent Malloggi, Patrick Guenoun 06/25/22 International Journal of Pharmaceutics
Huge solubility increase of poorly water-soluble pharmaceuticals by sulfobutylether-β-cyclodextrin complexation in a low-melting mixture François Xavier Legrand 06/01/22 Environmental Chemistry Letters
Defining Endocytic Pathways of Fucoidan-Coated PIBCA Nanoparticles from the Design of their Surface Architecture M. C.B. Lira-Nogueira, Christine Vauthier 06/01/22 Pharmaceutical Research
Oxidative Stress in Cancer Therapy: Friend or Enemy? Anaïs Pitto-Barry 05/18/22 ChemBioChem
Phospholipid-porphyrin conjugates: deciphering the driving forces behind their supramolecular assemblies Louis Gabriel Bronstein, Paul Cressey, Véronique Rosilio, Ali Makky 05/10/22 Nanoscale
Improving dexamethasone drug loading and efficacy in treating arthritis through a lipophilic prodrug entrapped into PLGA-PEG nanoparticles Rosana Simón-Vázquez, Nicolas Tsapis, Mathilde Lorscheider, Patricia Calleja, Ludivine Mousnier, Elias Fattal 05/01/22 Drug Delivery and Translational Research
Before in vivo studies: In vitro screening of sphingomyelin nanosystems using a relevant 3D multicellular pancreatic tumor spheroid model Nadège Bidan, Aure Vanhecke, S. Mura 04/05/22 International Journal of Pharmaceutics
One-Step Synthesis of Degradable Vinylic Polymer-Based Latexes via Aqueous Radical Emulsion Polymerization Maëlle Lages, Julien Nicolas 04/04/22 Angewandte Chemie - International Edition
Influence of the porphyrin structure and linker length on the interfacial behavior of phospholipid-porphyrin conjugates Louis Gabriel Bronstein, Paul Cressey, Véronique Rosilio, Ali Makky 04/01/22 Journal of Colloid and Interface Science
Highlighting the efficiency of ultrasound-based emulsifier-free emulsions to penetrate reconstructed human skin Yuri Dancik, Nicolas Huang 04/01/22 International Journal of Cosmetic Science
The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates Philippe M. Loiseau, Sébastien Pomel, Rémy Durand, Bruno Figadère 04/01/22 Molecules
Optimization of experimental conditions by surface enhanced Raman Scattering (SERS) spectroscopy with gold nanoparticles suspensions François Xavier Legrand 03/05/22 Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
A Simple Route to Aqueous Suspensions of Degradable Copolymer Nanoparticles Based on Radical Ring-Opening Polymerization-Induced Self-Assembly (rROPISA) Chen Zhu, Stéphanie Denis, Julien Nicolas 02/22/22 Chemistry of Materials
Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1 Clelia Mathieu, Elias Fattal, Juliette Vergnaud-Gauduchon 02/05/22 European Journal of Medicinal Chemistry
Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems Hicheme Hadji, Kawthar Bouchemal 02/01/22 Advanced Drug Delivery Reviews
Photo-triggerable liposomes based on lipid-porphyrin conjugate and cholesterol combination: Formulation and mechanistic study on monolayers and bilayers Julien Massiot, Ali Makky 02/01/22 Biochimica et Biophysica Acta - Biomembranes
Cubosomal lipid nanoassemblies with pH-sensitive shells created by biopolymer complexes: A synchrotron SAXS study Omar Mertins, Angelina Angelova 02/01/22 Journal of Colloid and Interface Science
Effect of micro- and nanoparticle shape on biological processes Hicheme Hadji, Kawthar Bouchemal 02/01/22 Journal of Controlled Release
The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target Didier Desmaële 02/01/22 Cell Death and Differentiation

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)