Aller au contenu principal

Biomarqueurs en cancérologie et onco-hématologie

Laboratory presentation

The research activities of the BECCOH laboratory concern clinical trials and the development of biomarkers, for patients with cutaneous, digestive or pulmonary cancers, or histocytoses. The laboratory's teams aim for strong cross-sections, particularly around the development and validation of predictive and prognostic biomarkers allowing an ever increasing specification of the therapeutic management of patients. The BECCOH laboratory has a histological and molecular pathology platform for the study of neoplasia, and is backed by a center of biological resources (CRB) certified by AFNOR to NF96-900 standard.

The 20 latest publications

Title Authors Publication date Source
Rational testing for gene fusion in colorectal cancer: MSI and RAS-BRAF wild-type metastatic colorectal cancer as target population for systematic screening Catherine Julié, Cristi Marin, Jean François Emile 07/01/22 European Journal of Cancer
Acute generalized exanthematous pustulosis caused by gemcitabine after nivolumab in metastatic lung adenocarcinoma followed by a dramatic tumor response: A case report Adrien Costantini, Etienne Giroux Leprieur 07/01/22 Thoracic Cancer
Investigation of the RB1-SOX2 axis constitutes a tool for viral status determination and diagnosis in Merkel cell carcinoma Astrid Blom, P. Saiag 06/01/22 Virchows Archiv
Tumor budding is an independent prognostic factor in stage III colon cancer patients: a post-hoc analysis of the IDEA-France phase III trial (PRODIGE-GERCOR) Jean François Emile 06/01/22 Annals of Oncology
Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in 78 patients from a single center Jean François Emile 06/01/22 Haematologica
Consensus statement by the French Society of Endocrinology (SFE) and French Society of Pediatric Endocrinology & Diabetology (SFEDP) on diagnosis of Cushing's syndrome Marie Laure Raffin-Samson 04/01/22 Annales d'Endocrinologie
MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis Jean François Emile, Omar I. Abdel-Wahab 04/01/22 Leukemia
Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma P. Saiag 04/01/22 Clinical Cancer Research
Monitoring of plasma concentrations of dabrafenib and trametinib in advanced BRAFV600<sup>mut</sup> melanoma patients M. Raynal, P. Saiag, E. Funck-Brentano 03/01/22 Annales de Dermatologie et de Venereologie
Impact of the French COVID-19 pandemic lockdown on newly diagnosed melanoma delay and severity A. Roger, Astrid Blom, C. Longvert, P. Saiag, E. Funck-Brentano 03/01/22 Journal of the European Academy of Dermatology and Venereology
<sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography imaging for the diagnosis of immune checkpoint inhibitor-associated myocarditis E. Funck-Brentano 02/01/22 Archives of Cardiovascular Diseases
A comprehensive overview of tumour deposits in colorectal cancer: Towards a next TNM classification Jean François Emile 02/01/22 Cancer Treatment Reviews
ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition Zofia Hélias-Rodzewicz, Jean Donadieu, Jean François Emile 01/13/22 Blood
Gene expression profile of high PD-L1 non-small cell lung cancers refractory to pembrolizumab Paul Takam Kamga, Marie Mayenga, Adrien Costantini, Catherine Julié, Jean François Emile, Etienne Giroux Leprieur 01/01/22 Cancer Immunology, Immunotherapy
Cutaneous histiocytoses in children Jean François Emile 01/01/22 Histopathology
Formalin-fixed tissue Mohs surgery (slow Mohs) for trichoblastic carcinoma B. Bonsang, U. Zimmermann, P. Saiag, E. Funck-Brentano 01/01/22 Journal of the European Academy of Dermatology and Venereology
High Circulating Sonic Hedgehog Protein Is Associated With Poor Outcome in EGFR-Mutated Advanced NSCLC Treated With Tyrosine Kinase Inhibitors Paul Takam Kamga, Adrien Costantini, Catherine Julié, Jean François Emile, Etienne Giroux Leprieur 12/14/21 Frontiers in Oncology
Maintenance of a Gastric Pacemaker in the Excluded Stomach During a Roux-en-Y Gastric Bypass Procedure in a Patient with Obesity, Type 1 Diabetes and Refractory Gastroparesis M. L. Raffin-Sanson 12/01/21 Obesity Surgery
Malignant histiocytosis with a Langerhans cell subtype: A report on the diagnostic and therapeutic challenge Jean François Emile 12/01/21 Blood Cells, Molecules, and Diseases
Cutaneous toxicities from targeted therapies used in oncology: Literature review of clinical presentation and management Solène Huynh Dagher, Astrid Blom, E. Funck-Brentano 12/01/21 International Journal of Women's Dermatology

Nombre de publications du laboratoire par domaine scientifique

Chaque publication du laboratoire peut être rangée dans une ou plusieurs disciplines scientifiques : la figure ci-dessus présente le nombre de publications du laboratoire pour chaque discipline de la classification ASJC (Elsevier)