Event date : from 4 November 2015 to 6 November 2015
Auditorium de l'Institut Curie, Bâtiment 111, Université Paris-Sud, Orsay

Cell imaging and microscopy play a prominent role in biological and medical research and have considerably progressed in the past fifteen years. Optical imaging techniques track the spatio-temporal transformations, interactions and dynamics of defined biomolecules in their functional context. A variety of chemical mapping methods give access to the biodistribution of cell metabolites as well as of exogenous drugs, nanocarriers or trace elements. Label-free or fast cryogenic methods better preserve living cell and tissue integrity, to analyze their subcellular as well as multicellular organization. Correlative approaches overlay various spectral or chemical information into high-content images. Most of these techniques now operate at or close to the molecular scale, i.e., at nanometric resolution.

From the single cell to the living animal, these advances will ultimately give access to a detailed, in situ physical and chemical analysis of biological functions, thereby addressing the challenge of biological complexity and integration. The intimate knowledge of biological processes thus gained at the molecular level brings in turn essential information for understanding and modeling diseases, opening the way to innovative therapeutic strategies.

The conference  will bring together an interdisciplinary community to discuss the latest advances in the fields of analytical cell imaging. Conference topics will cover cell signaling and trafficking studies, the development of new organic, inorganic or genetically encoded probes, innovative imaging contrasts and instruments, and will explore their potential for in vivo and biomedical applications.

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